Amorphous solid dispersions (ASDs) are a proven system for achieving a supersaturated
state of drug, in which the concentration of drug is greater than its crystalline solubility. The …

Cellulose derivatives have gained immense popularity as stabilizers for amorphous solid
dispersion owing to their diverse physicochemical properties. More than 20 amorphous solid …

The poor aqueous solubility of many active pharmaceutical ingredients (APIs) dominates
much of the early drug development portfolio and poses a major challenge in …

Given its health benefits to the human body, quercetin (QT) offers promising applications in
the healthcare food and pharmaceutical industries. However, the instability, low water …

Several drugs are pH-dependent soluble weak bases with a poor solubility in the intestinal
pH range. Additionally a variable gastric pH, which is a common issue in the population …

Site-specific modification is a great challenge for polysaccharide scientists. Chemo-and
regioselective modification of polysaccharide chains can provide many useful natural-based …

Hydroxypropyl methylcellulose acetate succinate (HPMCAS) has multi-disciplinary
applications spanning across the development of drug delivery systems, in 3D printing, and …

Polymer-based amorphous solid dispersions (ASDs) comprise one of the most promising
formulation strategies devised to improve the oral bioavailability of poorly water-soluble …

Solid dispersions of poorly-water soluble nifedipine using microparticles fabricated from
chitin biomass were prepared to improve the drug dissolution in an aqueous medium. After …

Copolymers synthesized from acrylic acid and methacrylic acid used as gastroprotective and
mucoadhesive enteric coatings have been used to prepare micro-(∼ 2 μm), submicro-(∼ …