RAD genes, known as double-strand break repair proteins, play a major role in maintaining
the genomic integrity of a cell by carrying out essential DNA repair functions via double …

Usher syndrome (USH) is a genetic disorder that is characterized by sensorineural hearing
loss (HL) and visual abnormality, ie, loss of night vision and side (peripheral) vision. Usher …

Intellectual disability, a genetically and clinically varied disorder and is a significant health
problem, particularly in less developed countries due to larger family size and high ratio of …

Background: Comorbid chronic neuropathic pain (NPP) and anxio-depressive disorders
(ADD) have become a serious global public-health problem. The SLIT and NTRK-like 1 …

Background Diabetes type 1 is an autoimmune metabolic disorder in which auto antibodies
attack pancreatic β cells, results in hyperglycemia. Diabetes retinopathy linked to diabetes …

Intellectual disability (ID) is a neuro-developmental condition that affects a person's cognitive
ability and results in a learning defect. It affects 1–3% of the general population; however …

Intellectual disability (ID) is a neuro-developmental condition that affects a person's cognitive
ability and results in a learning defect. It affects 1–3% of the general population; however …

The human genome innovation is becoming more accessible owing to breakthroughs in
DNA sequencing. Due to the massive variety of mutations, interpreting genetic variation is …

In the present study, we performed in silico analysis on all reported mutations of PRODH in
order to investigate their biological significance. 3D models of wildtype and mutant PRODH …

LGMDR1 is a type of Limb Girdle Muscular Dystrophy (LGMD) with an autosomal recessive
inherited prevalence ranging from 0.001% to 0.009% cases. It affects approximately 30% of …