Effective screening modalities are currently available for only a small subset of cancers, and
they generally have suboptimal performance with complicated procedures. Therefore, there …

Simple Summary Anoikis is a programmed cell death process resulting from the loss of
interaction between cells and the extracellular matrix. Therefore, it is necessary to overcome …

MicroRNAs (miRNAs) are gene regulators involved in the pathogenesis of complex
diseases such as cancers, and thus serve as potential diagnostic markers and therapeutic …

We review research regarding the epidemiology, risk factors, genetic susceptibility,
molecular pathology, and early detection of SCLC, a deadly tumor that accounts for 14% of …

Circular RNA (circRNA) is a novel class of single-stranded RNAs with a closed loop
structure. The majority of circRNAs are formed by a back-splicing process in pre-mRNA …

Simple Summary Lung cancer is a widespread malignant tumour with a high mortality and
morbidity rate and is frequently diagnosed in the middle and late stages when few therapies …

A lack of promising targets leads to poor prognosis in patients with lung adenocarcinoma
(LUAD). Therefore, it is urgent to identify novel therapeutic targets. The importance of the N 6 …

Aging is a key risk factor for chronic diseases of the elderly. MicroRNAs regulate post-
transcriptional gene silencing through base-pair binding on their target mRNAs. We …

Simple Summary Apart from genetic changes, cancer is characterized by epigenetic
alterations, which indicate modifications in the DNA (such as DNA methylation) and histones …

Simple Summary Lung cancer is the leading cause of cancer death worldwide. Detecting
lung malignancies promptly is essential for any anticancer treatment to reduce mortality and …