SUMOylation, a post-translational modification involving the covalent attachment of small
ubiquitin-like modifier (SUMO) proteins to target substrates, plays a pivotal role at the …

Simple Summary The cell nucleus is organized into different sub-nuclear compartments to
control specific cellular processes, including PML nuclear bodies (NBs), also termed PML …

Abstract Both vitamin D 3 (VD 3) and zinc (Zn) are essential micronutrients to fish, and VD 3
can regulate Zn uptake and metabolism in various animals. However, the interactive effect of …

Zinc plays a central role in the hematological development. Therapeutic interventions with
zinc are shown to improve the health status of patients with malignancies by stimulating the …

Here, we present a novel strategy that integrates genetic-code expansion and proximity-
induced crosslinking to achieve site-specific in vivo SUMOylation. This approach involves …

Abstract SUMO (Small Ubiquitin‐like Modifiers) proteins are involved in a crucial post‐
translational modification commonly termed as SUMOylation. In this work, we have …

Small Ubiquitin-related modifiers of the SUMO family regulate thousands of proteins in
eukaryotic cells. Many SUMO substrates, effectors and enzymes carry short motifs (SIMs) …