Artificial intelligence-based multi-omics analysis fuels cancer precision medicine

X He, X Liu, F Zuo, H Shi, J **g - Seminars in Cancer Biology, 2023 - Elsevier
With biotechnological advancements, innovative omics technologies are constantly
emerging that have enabled researchers to access multi-layer information from the genome …

To metabolomics and beyond: a technological portfolio to investigate cancer metabolism

F Danzi, R Pacchiana, A Mafficini, MT Scupoli… - … and Targeted Therapy, 2023 - nature.com
Tumour cells have exquisite flexibility in reprogramming their metabolism in order to support
tumour initiation, progression, metastasis and resistance to therapies. These reprogrammed …

A cuproptosis nanocapsule for cancer radiotherapy

Y Liao, D Wang, C Gu, X Wang, S Zhu, Z Zheng… - Nature …, 2024 - nature.com
Residual tumours that persist after radiotherapy often develop acquired radiation resistance,
increasing the risk of recurrence and metastasis while providing obstacles to re-irradiation …

Dissecting metastasis using preclinical models and methods

JD Hebert, JW Neal, MM Winslow - Nature Reviews Cancer, 2023 - nature.com
Metastasis has long been understood to lead to the overwhelming majority of cancer-related
deaths. However, our understanding of the metastatic process, and thus our ability to …

Prognostic implication of plasma metabolites in gastric cancer

K Cao, Y Lyu, J Chen, C He, X Lyu, Y Zhang… - International Journal of …, 2023 - mdpi.com
Gastric cancer (GC) typically carries a poor prognosis as it is often diagnosed at a late stage.
Altered metabolism has been found to impact cancer outcomes and affect patients' quality of …

Nonmonotone invasion landscape by noise-aware control of metastasis activator levels

Y Wan, J Cohen, M Szenk, KS Farquhar… - Nature Chemical …, 2023 - nature.com
A major pharmacological assumption is that lowering disease-promoting protein levels is
generally beneficial. For example, inhibiting metastasis activator BACH1 is proposed to …

Dual-source powered nanomotors coupled with dual-targeting ligands for efficient capture and detection of CTCs in whole blood and in vivo tumor imaging

J Ren, Z Chen, E Ma, W Wang, S Zheng… - Colloids and Surfaces B …, 2023 - Elsevier
Circulating tumor cells (CTCs) are important biomarkers in cancer diagnosis. However, the
specific labeling of CTCs with high capture efficiency in whole blood remains a problem …

Metabolomics and cellular altered pathways in cancer biology: A review

JK Bhardwaj, A Siwach… - Journal of Biochemical …, 2024 - Wiley Online Library
Cancer is a deadly disease that affects a cell's metabolism and surrounding tissues.
Understanding the fundamental mechanisms of metabolic alterations in cancer cells would …

The Role of Stroma in Cancer Metabolism

AC Kimmelman, MH Sherman - Cold Spring …, 2024 - perspectivesinmedicine.cshlp.org
The altered metabolism of tumor cells is a well-known hallmark of cancer and is driven by
multiple factors such as mutations in oncogenes and tumor suppressor genes, the origin of …

The Clinical Impact of Time-restricted Eating on Cancer: A Systematic Review

EJ Stringer, RWG Cloke, L Van der Meer… - Nutrition …, 2024 - academic.oup.com
Context In the face of the growing global burden of cancer, there is increasing interest in
dietary interventions to mitigate its impacts. Pre-clinical evidence suggests that time …