Role of endothelial dysfunction in cardiovascular diseases: the link between inflammation and hydrogen sulfide

HJ Sun, ZY Wu, XW Nie, JS Bian - Frontiers in pharmacology, 2020 - frontiersin.org
Endothelial cells are important constituents of blood vessels that play critical roles in
cardiovascular homeostasis by regulating blood fluidity and fibrinolysis, vascular tone …

[HTML][HTML] Hydrogen sulfide and vascular regulation–An update

B Lv, S Chen, C Tang, H **, J Du, Y Huang - Journal of advanced research, 2021 - Elsevier
Abstract Background Hydrogen sulfide (H 2 S) is considered to be the third gasotransmitter
after carbon monoxide (CO) and nitric oxide (NO). It plays an important role in the regulation …

Expanding the frontiers of guardian antioxidant selenoproteins in cardiovascular pathophysiology

T Angelone, C Rocca, V Lionetti, C Penna… - Antioxidants & Redox …, 2024 - liebertpub.com
Significance: Physiological levels of reactive oxygen and nitrogen species (ROS/RNS)
function as fundamental messengers for many cellular and developmental processes in the …

Targeting epigenetics and non-coding RNAs in atherosclerosis: from mechanisms to therapeutics

S Xu, D Kamato, PJ Little, S Nakagawa… - Pharmacology & …, 2019 - Elsevier
Atherosclerosis, the principal cause of cardiovascular death worldwide, is a pathological
disease characterized by fibro-proliferation, chronic inflammation, lipid accumulation, and …

DNA methylation and histone post-translational modifications in atherosclerosis and a novel perspective for epigenetic therapy

L Zhang, C **a, Y Yang, F Sun, Y Zhang… - Cell Communication and …, 2023 - Springer
Atherosclerosis, which is a vascular pathology characterized by inflammation and plaque
build-up within arterial vessel walls, acts as the important cause of most cardiovascular …

Hydrogen Sulfide (H2S)-Releasing Compounds: Therapeutic Potential in Cardiovascular Diseases

L Zhang, Y Wang, Y Li, L Li, S Xu, X Feng… - Frontiers in …, 2018 - frontiersin.org
Cardiovascular disease is the main cause of death worldwide, but its pathogenesis is not yet
clear. Hydrogen sulfide (H2S) is considered to be the third most important endogenous …

[HTML][HTML] Pharmacological modulation of vascular ageing: a review from VascAgeNet

L Roth, S Dogan, BG Tuna, T Aranyi, S Benitez… - Ageing research …, 2023 - Elsevier
Vascular ageing, characterized by structural and functional changes in blood vessels of
which arterial stiffness and endothelial dysfunction are key components, is associated with …

[HTML][HTML] Biological functions of hydrogen sulfide in plants

Z Yang, X Wang, J Feng, S Zhu - International Journal of Molecular …, 2022 - mdpi.com
Hydrogen sulfide (H2S), which is a gasotransmitter, can be biosynthesized and participates
in various physiological and biochemical processes in plants. H2S also positively affects …

Upregulation of MDH1 acetylation by HDAC6 inhibition protects against oxidative stress-derived neuronal apoptosis following intracerebral hemorrhage

M Wang, C Zhou, L Yu, D Kong, W Ma, B Lv… - Cellular and Molecular …, 2022 - Springer
Oxidative stress impairs functional recovery after intracerebral hemorrhage (ICH). Histone
deacetylase 6 (HDAC6) plays an important role in the initiation of oxidative stress. However …

Protein S-sulfhydration: Unraveling the prospective of hydrogen sulfide in the brain, vasculature and neurological manifestations

R Gupta, M Sahu, R Tripathi, RK Ambasta… - Ageing Research …, 2022 - Elsevier
Hydrogen sulfide (H 2 S) and hydrogen polysulfides (H 2 S n) are essential regulatory
signaling molecules generated by the entire body, including the central nervous system …