Protein assembly by design

J Zhu, N Avakyan, A Kakkis, AM Hoffnagle… - Chemical …, 2021 - ACS Publications
Proteins are nature's primary building blocks for the construction of sophisticated molecular
machines and dynamic materials, ranging from protein complexes such as photosystem II …

Cucurbituril‐based biomacromolecular assemblies

YH Liu, YM Zhang, HJ Yu, Y Liu - Angewandte Chemie, 2021 - Wiley Online Library
The construction of controlled biomacromolecular assemblies has become a thriving area of
supramolecular chemistry. In this context, cucurbiturils (CBs), a class of macrocyclic …

Self-sorted, random, and block supramolecular copolymers via sequence controlled, multicomponent self-assembly

A Sarkar, R Sasmal, C Empereur-Mot… - Journal of the …, 2020 - ACS Publications
Multicomponent supramolecular copolymerization promises to construct complex
nanostructures with emergent properties. However, even with two monomeric components …

A general picture of cucurbit [8] uril host–guest binding

Z Sun, Z Huai, Q He, Z Liu - Journal of chemical information and …, 2021 - ACS Publications
Describing, understanding, and designing complex interaction networks within
macromolecular systems remain challenging in modern chemical research. Host–guest …

Cucurbit [7] uril macrocyclic sensors for optical fingerprinting: predicting protein structural changes to identifying disease-specific amyloid assemblies

N Das Saha, S Pradhan, R Sasmal… - Journal of the …, 2022 - ACS Publications
In a three-dimensional (3D) representation, each protein molecule displays a specific
pattern of chemical and topological features, which are altered during its misfolding and …

Selective Molecular Recognition and Indicator Displacement Sensing of Neurotransmitters in Cellular Environments

J Chen, EZ Tabaie, BL Hickey, Z Gao, AAP Raz… - ACS …, 2023 - ACS Publications
Flexible, water-soluble hosts are capable of selective molecular recognition in cellular
environments and can detect neurotransmitters such as choline in cells. Both cationic and …

Protein‐Based Controllable Nanoarchitectonics for Desired Applications

L Li, Y Zhang, Y Wu, Z Wang, W Cui… - Advanced Functional …, 2024 - Wiley Online Library
Controllable protein nanoarchitectonics refers to the process of manipulating and controlling
the assembly of proteins at the nanoscale to achieve domain‐limited and accurate spatial …

Supramolecular Guest Exchange in Cucurbit [7] uril for Bioorthogonal Fluorogenic Imaging across the Visible Spectrum

R Sasmal, A Som, P Kumari, RV Nair, S Show… - ACS Central …, 2024 - ACS Publications
Fluorogenic probes that unmask fluorescence signals in response to bioorthogonal
reactions are a powerful new addition to biological imaging. They can significantly reduce …

Multiplexed optical barcoding of cells via photochemical programming of bioorthogonal host–guest recognition

A Som, M Pahwa, S Bawari, ND Saha, R Sasmal… - Chemical …, 2021 - pubs.rsc.org
Modern chemical and biological studies are undergoing a paradigm shift, where
understanding the fate of individual cells, in an apparently homogeneous population, is …

Binding affinity-based intracellular drug detection enabled by a unimolecular cucurbit [7] uril-dye conjugate

Y Liu, C Hu, JA Serna, F Biedermann… - RSC Chemical Biology, 2023 - pubs.rsc.org
Label-free fluorescence-based chemosensing has been increasingly brought into focus due
to its simplicity and high sensitivity for intracellular monitoring of molecules. Currently used …