Temporal lobe epilepsy (TLE) is frequently associated with hippocampal sclerosis, possibly
caused by a primary brain injury that occurred a long time before the appearance of …

New neurons are continuously generated in two adult brain regions: the subgranular zone of
the hippocampus and the subependyma by the lateral ventricles, referred to as the …

Status epilepticus (SE), a medical emergency that is typically terminated through
antiepileptic drug treatment, leads to hippocampus dysfunction typified by …

The phosphatidylinositol-3-kinase/phosphatase and tensin homolog (PTEN)-mammalian
target of rapamycin (mTOR) pathway regulates a variety of neuronal functions, including cell …

Medial ganglionic eminence (MGE)-like interneuron precursors derived from human
induced pluripotent stem cells (hiPSCs) are ideal for develo** patient-specific cell therapy …

Impairments in mood and cognitive function are the key brain abnormalities observed in Gulf
war illness (GWI), a chronic multisymptom health problem afflicting∼ 25% of veterans who …

Understanding the mechanisms behind neurodifferentiation in adults will be an important
milestone in our quest to identify treatment strategies for cognitive disorders observed during …

Depression is a major health issue that causes severe societal economic and health burden.
Aromatherapy, a practice that uses essential oils for preventive and therapeutic purposes …

The hippocampal dentate gyrus maintains its capacity to generate new neurons throughout
life. In animal models, hippocampal neurogenesis is increased by cognitive tasks, and …

Epilepsy and depression share an unusually high coincidence suggestive of a common
etiology. Disrupted production of adult-born hippocampal granule cells in both disorders …