Testosterone–the gonadal sex steroid hormone plays an important role in the central
nervous system (CNS) development. One of the less known testosterone actions is …

Prostate cancer is the second most common form of cancer in men. For advanced, high risk
prostate cancer, androgen deprivation therapy (ADT) is the preferred treatment and can …

The aim of the study was to examine the effects of two‐year testosterone replacement
therapy on cognitive functioning, emotional state and quality of life in young and middle …

The study aimed to analyse emotional state, quality of life and cognitive functions in young
hypogonadal men. Thirty‐four males with hypogonadism (age 29.1±10.5 years) and 34 age …

Transthyretin (TTR) is a 55 kDa plasma homotetrameric protein mainly synthesized in the
liver and choroid plexuses (CPs) of the brain that, functions as a carrier for thyroxin and …

A review of the literature in both animals and humans reveals that changes in sex hormone
have often been associated with changes in behavioral and mental abilities. Previously …

ABSTRACT Primary Objective Traumatic brain injury (TBI) is associated with higher
incidence of neurodegenerative disease and the effects of aging appear more pronounced …

Cognition enhancers are drugs able to facilitate attentional abilities and acquisition, storage
and retrieval of information, and to attenuate the impairment of cognitive functions …

The purpose of this chapter is to consider whether clinical interventions might evolve toward
restitution of normalized metabolic and neurophysiologic activity following traumatic insult to …

The contemporary advances in neuroscience and anti-aging medicine show that the brain
and nervous system can adapt to chronic stress, inflammation and damage mechanisms by …