MALDI-MSI towards multimodal imaging: challenges and perspectives

M Tuck, F Grélard, L Blanc, N Desbenoit - Frontiers in Chemistry, 2022 - frontiersin.org
Multimodal imaging is a powerful strategy for combining information from multiple images. It
involves several fields in the acquisition, processing and interpretation of images. As …

Desorption electrospray ionization mass spectrometry imaging (DESI-MSI) in disease diagnosis: an overview

BS Kumar - Analytical Methods, 2023 - pubs.rsc.org
Tissue analysis, which is essential to histology and is considered the benchmark for the
diagnosis and prognosis of many illnesses, including cancer, is significant. During surgery …

Nano-DESI mass spectrometry imaging of proteoforms in biological tissues with high spatial resolution

M Yang, D Unsihuay, H Hu, F Nguele Meke… - Analytical …, 2023 - ACS Publications
Mass spectrometry imaging (MSI) is a powerful tool for label-free map** of the spatial
distribution of proteins in biological tissues. We have previously demonstrated imaging of …

Recent review on selected xenobiotics and their impacts on gut microbiome and metabolome

Y **, J Chi, K LoMonaco, A Boon, H Gu - TrAC Trends in Analytical …, 2023 - Elsevier
As it is well known, the gut is one of the primary sites in any host for xenobiotics, and the
many microbial metabolites responsible for the interactions between the gut microbiome and …

Quantification of nitric oxide in single cells using the single-probe mass spectrometry technique

Y Lan, X Chen, Z Yang - Analytical Chemistry, 2023 - ACS Publications
Nitric oxide (NO) is a small molecule that plays important roles in biological systems and
human diseases. The abundance of intracellular NO is tightly related to numerous biological …

Advances and emerging medical applications of direct mass spectrometry technologies for tissue analysis

ME King, M Lin, M Spradlin… - Annual Review of …, 2023 - annualreviews.org
Offering superb speed, chemical specificity, and analytical sensitivity, direct mass
spectrometry (MS) technologies are highly amenable for the molecular analysis of complex …

Exploring natural product biosynthesis in plants with mass spectrometry imaging

Y Zou, W Tang, B Li - Trends in Plant Science, 2024 - cell.com
The biosynthesis of natural products (NPs) is a complex dynamic spatial and temporal
process that requires the collaboration of multiple disciplines to explore the underlying …

Imaging with mass spectrometry: Which ionization technique is best?

BM Prentice - Journal of Mass Spectrometry, 2024 - Wiley Online Library
The use of mass spectrometry (MS) to acquire molecular images of biological tissues and
other substrates has developed into an indispensable analytical tool over the past 25 years …

[HTML][HTML] Advanced progress of spatial metabolomics in head and neck cancer research

H Zhao, C Shi, W Han, G Luo, Y Huang, Y Fu, W Lu… - Neoplasia, 2024 - Elsevier
Head and neck cancer ranks as the sixth most prevalent malignancy, constituting 5% of all
cancer cases. Its inconspicuous onset often leads to advanced stage diagnoses, prompting …

Mass spectrometry imaging: new eyes on natural products for drug research and development

J Hou, Z Zhang, W Wu, Q He, T Zhang, Y Liu… - Acta Pharmacologica …, 2022 - nature.com
Natural products (NPs) and their structural analogs represent a major source of novel drug
development for disease prevention and treatment. The development of new drugs from NPs …