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Opioids and cardiac arrhythmia: a literature review
Objective: One of the most important side effects of opioids is their influence on the electrical
activity of the heart. This review focusses on the effects of opioids on QT interval …
activity of the heart. This review focusses on the effects of opioids on QT interval …
A systematic review of the cardiotoxicity of methadone
S Alinejad, T Kazemi, N Zamani, RS Hoffman… - EXCLI …, 2015 - pmc.ncbi.nlm.nih.gov
Methadone is one of the most popular synthetic opioids in the world with some favorable
properties making it useful both in the treatment of moderate to severe pain and for opioid …
properties making it useful both in the treatment of moderate to severe pain and for opioid …
[HTML][HTML] Methadone overdose and cardiac arrhythmia potential: findings from a review of the evidence for an American Pain Society and College on Problems of Drug …
R Chou, MB Weimer, T Dana - The Journal of Pain, 2014 - Elsevier
The number of deaths associated with methadone use increased dramatically in parallel
with marked increases in its use, particularly for treatment of chronic pain. To develop a …
with marked increases in its use, particularly for treatment of chronic pain. To develop a …
Clinical and metabolic responses to crocin in patients under methadone maintenance treatment: A randomized clinical trial
A Ghaderi, M Rasouli‐Azad, N Vahed… - Phytotherapy …, 2019 - Wiley Online Library
Patients under methadone maintenance treatment (MMT) programs are susceptible to
several complications including metabolic and clinical disorders. This study was designed to …
several complications including metabolic and clinical disorders. This study was designed to …
QTc interval screening for cardiac risk in methadone treatment of opioid dependence
PP Pani, E Trogu, I Maremmani… - Cochrane Database of …, 2013 - cochranelibrary.com
Background Methadone represents today the gold standard of efficacy for the
pharmacological treatment of opioid dependence. Methadone, like many other medications …
pharmacological treatment of opioid dependence. Methadone, like many other medications …
Methadone maintenance, QTc and torsade de pointes: who needs an electrocardiogram and what is the prevalence of QTc prolongation?
S Mayet, M Gossop, N Lintzeris… - Drug and alcohol …, 2011 - Wiley Online Library
Abstract Introduction and Aims. High‐dose methadone has been associated with rate‐
corrected QT (QTc) prolongation and 'torsade de pointes'. The Medicines and Healthcare …
corrected QT (QTc) prolongation and 'torsade de pointes'. The Medicines and Healthcare …
Corrected QT interval during treatment with methadone and buprenorphine—Relation to doses and serum concentrations
M Stallvik, B Nordstrand, Ø Kristensen, J Bathen… - Drug and alcohol …, 2013 - Elsevier
BACKGROUND: Methadone and buprenorphine are widely used in the treatment of opioid
addiction. Some study results suggest that methadone can be associated with QT interval …
addiction. Some study results suggest that methadone can be associated with QT interval …
Functional Genetic Polymorphisms in CYP2C19 Gene in Relation to Cardiac Side Effects and Treatment Dose in a Methadone Maintenance Cohort
SC Wang, IK Ho, HH Tsou, SW Liu… - Omics: a journal of …, 2013 - liebertpub.com
Methadone maintenance therapy is an established treatment for heroin dependence. This
study tested the influence of functional genetic polymorphisms in CYP2C19 gene encoding …
study tested the influence of functional genetic polymorphisms in CYP2C19 gene encoding …