Pathology of the vulnerable plaque
R Virmani, AP Burke, A Farb, FD Kolodgie - Journal of the American …, 2006 - jacc.org
The majority of patients with acute coronary syndromes (ACS) present with unstable angina,
acute myocardial infarction, and sudden coronary death. The most common cause of …
acute myocardial infarction, and sudden coronary death. The most common cause of …
Inflammation as a cardiovascular risk factor
JT Willerson, PM Ridker - Circulation, 2004 - Am Heart Assoc
Inflammation occurs in the vasculature as a response to injury, lipid peroxidation, and
perhaps infection. Various risk factors, including hypertension, diabetes, and smoking, are …
perhaps infection. Various risk factors, including hypertension, diabetes, and smoking, are …
[HTML][HTML] Physiological factors characterizing heat-vulnerable older adults: a narrative review
More frequent and intense periods of extreme heat (heatwaves) represent the most direct
challenge to human health posed by climate change. Older adults are particularly …
challenge to human health posed by climate change. Older adults are particularly …
Passive and active drug targeting: drug delivery to tumors as an example
VP Torchilin - Drug delivery, 2010 - Springer
The paradigm of using nanoparticulate pharmaceutical carriers has been well established
over the past decade, both in pharmaceutical research and in the clinical setting. Drug …
over the past decade, both in pharmaceutical research and in the clinical setting. Drug …
Extracranial thrombotically active carotid plaque as a risk factor for ischemic stroke
LG Spagnoli, A Mauriello, G Sangiorgi, S Fratoni… - Jama, 2004 - jamanetwork.com
ContextRecent studies suggest that factors other than the degree of carotid stenosis are
involved in ischemic stroke pathogenesis, especially modifications of plaque composition …
involved in ischemic stroke pathogenesis, especially modifications of plaque composition …
Detection of vulnerable coronary plaques using invasive and non-invasive imaging modalities
A van Veelen, NMR van der Sangen, R Delewi… - Journal of clinical …, 2022 - mdpi.com
Acute coronary syndrome (ACS) mostly arises from so-called vulnerable coronary plaques,
particularly prone for rupture. Vulnerable plaques comprise a specific type of plaque, called …
particularly prone for rupture. Vulnerable plaques comprise a specific type of plaque, called …
Diffuse and active inflammation occurs in both vulnerable and stable plaques of the entire coronary tree: a histopathologic study of patients dying of acute myocardial …
Objectives: This study was undertaken to define and compare geographic coronary artery
inflammation in patients who were dying of acute myocardial infarction (AMI), chronic stable …
inflammation in patients who were dying of acute myocardial infarction (AMI), chronic stable …
Imaging the vulnerable plaque
Cardiovascular diseases are still the primary causes of mortality in the United States and in
Western Europe. Arterial thrombosis is triggered by a ruptured atherosclerotic plaque and …
Western Europe. Arterial thrombosis is triggered by a ruptured atherosclerotic plaque and …
Selective clearance of macrophages in atherosclerotic plaques by autophagy
Objectives: The purpose of this study was to investigate whether stent-based delivery of an
inhibitor of mammalian target of rapamycin (mTOR) can selectively clear macrophages in …
inhibitor of mammalian target of rapamycin (mTOR) can selectively clear macrophages in …
Targeting macrophages with multifunctional nanoparticles to detect and prevent atherosclerotic cardiovascular disease
V Nankivell, AK Vidanapathirana… - Cardiovascular …, 2024 - academic.oup.com
Despite the emergence of novel diagnostic, pharmacological, interventional, and prevention
strategies, atherosclerotic cardiovascular disease remains a significant cause of morbidity …
strategies, atherosclerotic cardiovascular disease remains a significant cause of morbidity …