Macrophages and the maintenance of homeostasis

DM Mosser, K Hamidzadeh, R Goncalves - Cellular & molecular …, 2021‏ - nature.com
There have been many chapters written about macrophage polarization. These chapters
generally focus on the role of macrophages in orchestrating immune responses by …

Regulation of coronary blood flow

AG Goodwill, GM Dick, AM Kiel… - Comprehensive …, 2017‏ - pmc.ncbi.nlm.nih.gov
The heart is uniquely responsible for providing its own blood supply through the coronary
circulation. Regulation of coronary blood flow is quite complex and, after over 100 years of …

Reactive hyperemia: a review of methods, mechanisms, and considerations

R Rosenberry, MD Nelson - American Journal of …, 2020‏ - journals.physiology.org
Reactive hyperemia is a well-established technique for noninvasive assessment of
peripheral microvascular function and a predictor of all-cause and cardiovascular morbidity …

Metabolic shifts in immunity and inflammation

DJ Kominsky, EL Campbell… - The Journal of Immunology, 2010‏ - journals.aai.org
Sites of ongoing inflammation and triggered immune responses are characterized by
significant changes in metabolic activity. Recent studies have indicated that such shifts in …

Escin: A review of its anti-edematous, anti-inflammatory, and venotonic properties

L Gallelli - Drug design, development and therapy, 2019‏ - Taylor & Francis
This review discusses historical and recent pharmacological and clinical data on the anti-
edematous, anti-inflammatory, and venotonic properties of escin (Reparil®). Escin, the …

Therapeutic potential of natural compounds in inflammation and chronic venous insufficiency

A Lichota, L Gwozdzinski, K Gwozdzinski - European Journal of Medicinal …, 2019‏ - Elsevier
The term varicose vein refers to the twisted and swollen vein visible under the skin surface
which occurs most commonly in the leg. Epidemiological studies report a varying …

The blood-brain barrier in neuroinflammatory diseases

HE De Vries, J Kuiper, AG De Boer… - Pharmacological …, 1997‏ - pharmrev.aspetjournals.org
The existence of the blood-brain barrier (BBB) b was revealed through studies by Ehrlich
(1885) in the late 19th century, describing that brain tissue remained unstained after …

Hypoxia induces cyclooxygenase-2 via the NF-κB p65 transcription factor in human vascular endothelial cells

JF Schmedtje, YS Ji, WL Liu, RN DuBois… - Journal of Biological …, 1997‏ - jbc.org
The inducible cyclooxygenase, COX-2, has been associated with vascular inflammation and
cellular proliferation. We have discovered that hypoxia increases expression of the COX-2 …

Inflammatory mediators of cerebral endothelium: a role in ischemic brain inflammation

D Stanimirovic, K Satoh - Brain pathology, 2000‏ - Wiley Online Library
Brain inflammation has been implicated in the development of brain edema and secondary
brain damage in ischemia and trauma. Adhesion molecules, cytokines and leukocyte …

The prognostic value of muscle StO2 in septic patients

J Creteur, T Carollo, G Soldati, G Buchele… - Intensive care …, 2007‏ - Springer
Objective: To quantify sepsis-induced alterations in changes in muscle tissue oxygenation
(StO 2) after an ischemic challenge using near-infrared spectroscopy (NIRS), and to test the …