Diagnosis and treatment of pulmonary arterial hypertension: a review

NF Ruopp, BA Cockrill - Jama, 2022 - jamanetwork.com
Importance Pulmonary arterial hypertension (PAH) is a subtype of pulmonary hypertension
(PH), characterized by pulmonary arterial remodeling. The prevalence of PAH is …

Pulmonary arterial hypertension: pathogenesis and clinical management

T Thenappan, ML Ormiston, JJ Ryan, SL Archer - Bmj, 2018 - bmj.com
Pulmonary hypertension is defined as a resting mean pulmonary artery pressure of 25 mm
Hg or above. This review deals with pulmonary arterial hypertension (PAH), a type of …

[HTML][HTML] Haemodynamic definitions and updated clinical classification of pulmonary hypertension

G Simonneau, D Montani… - European respiratory …, 2019 - Eur Respiratory Soc
Since the 1st World Symposium on Pulmonary Hypertension (WSPH) in 1973, pulmonary
hypertension (PH) has been arbitrarily defined as mean pulmonary arterial pressure …

Pulmonary arterial hypertension: diagnosis, treatment, and novel advances

BA Maron, SH Abman, CG Elliott, RP Frantz… - American journal of …, 2021 - atsjournals.org
The diagnosis and management of pulmonary arterial hypertension (PAH) includes several
advances, such as a broader recognition of extrapulmonary vascular organ system …

Discovery of distinct immune phenotypes using machine learning in pulmonary arterial hypertension

AJ Sweatt, HK Hedlin, V Balasubramanian… - Circulation …, 2019 - Am Heart Assoc
Rationale: Accumulating evidence implicates inflammation in pulmonary arterial
hypertension (PAH) and therapies targeting immunity are under investigation, although it …

Harnessing big data to advance treatment and understanding of pulmonary hypertension

CJ Rhodes, AJ Sweatt, BA Maron - Circulation research, 2022 - Am Heart Assoc
Pulmonary hypertension is a complex disease with multiple causes, corresponding to
phenotypic heterogeneity and variable therapeutic responses. Advancing understanding of …

Systems analysis of the human pulmonary arterial hypertension lung transcriptome

RS Stearman, QM Bui, G Speyer, A Handen… - American journal of …, 2019 - atsjournals.org
Pulmonary arterial hypertension (PAH) is characterized by increased pulmonary artery
pressure and vascular resistance, typically leading to right heart failure and death. Current …

Translational Advances in the Field of Pulmonary Hypertension.From Cancer Biology to New Pulmonary Arterial Hypertension Therapeutics. Targeting Cell Growth …

SS Pullamsetti, R Savai, W Seeger… - American journal of …, 2017 - atsjournals.org
Pulmonary arterial hypertension (PAH) has been frequently compared with a type of
malignant disease and has an incredible number of pathogenic mechanisms similar to …

Association Between Circulating CD4+ T Cell Methylation Signatures of Network-Oriented SOCS3 Gene and Hemodynamics in Patients Suffering Pulmonary Arterial …

G Benincasa, BA Maron, O Affinito, M D'Alto… - Journal of …, 2023 - Springer
Pathogenic DNA methylation changes may be involved in pulmonary arterial hypertension
(PAH) onset and its progression, but there is no data on potential associations with patient …

[HTML][HTML] 2020 Clinical practice guidelines for Pulmonary hypertension, including chronic thromboembolic pulmonary hypertension

SN Avdeev, OL Barbarash, AE Bautin… - Russian Journal of …, 2021 - russjcardiol.elpub.ru
2020 Clinical practice guidelines for Pulmonary hypertension, including chronic thromboembolic
pulmonary hypertension | Avdeev | Russian Journal of Cardiology Russian Journal of …