Frailty, a consequence of the interaction of the aging process and certain chronic diseases,
compromises functional outcomes in the elderly and substantially increases their risk for …

Functional status is considered the main determinant of healthy aging. Impairment in
skeletal muscle and the cardiovascular system, two interrelated systems, results in …

The human ageing process is universal, ubiquitous and inevitable. Every physiological
function is being continuously diminished. There is a range between two distinct phenotypes …

Abstract Objective To develop Clinical Practice Guidelines for the screening, assessment
and management of the geriatric condition of frailty. Methods An adapted Grading of …

Background Physical exercise is an effective strategy for preserving functional capacity and
improving the symptoms of frailty in older adults. In addition to functional gains, exercise is …

Physical function (ie, aerobic capacity, gait speed, and muscle strength) has been proposed
as a biomarker of healthy ageing, as it is predictive of adverse health events, disability, and …

Introduction Skeletal muscle power has been demonstrated to be a stronger predictor of
functional limitations than any other physical capability. However, no validated alternatives …

Exercise and physical activity offer clinical benefits across a wide range of both physical and
neuropsychological diseases and disabilities in older adults, including syndromes for which …

Frailty syndrome encompasses several physical hallmarks such as loss of muscle strength,
power output and mass, which leads to poor gait ability, fatigue, falls and overall difficulty to …

Aging, a universal and inevitable process, is characterized by a progressive accumulation of
physiological alterations and functional decline over time, leading to increased vulnerability …