A century ago, the Warburg effect was first proposed, revealing that cancer cells
predominantly rely on glycolysis during the process of tumorigenesis, even in the presence …

Mesenchymal stem cells based therapy has been used in clinic for almost 20 years and has
shown encouraging effects in treating a wide range of diseases. However, the underlying …

Ovarian cancer is characterized by early metastatic spread. This study demonstrates that
carcinoma-associated mesenchymal stromal cells (CA-MSCs) enhance metastasis by …

Pulmonary fibrosis (PF) is an interstitial lung disease tightly associated with the disruption of
mitochondrial pool homeostasis, a delicate balance influenced by functional and …

Background: Exercise can promote sustainable protection against cold and warm liver
ischemia–reperfusion injury (IRI) and tumor metastases. We have shown that this protection …

The cancer paradigm is generally based on the somatic mutation model, asserting that
cancer is a disease of genetic origin. The mitochondrial–stem cell connection (MSCC) …

The ionizing radiation (IR) represents a formidable challenge as an environmental factor to
mitochondria, leading to disrupt cellular energy metabolism and posing health risks …

Generally, Cryptococcus initially infects the respiratory tract, but can spread, eventually
crossing the blood-brain barrier (BBB) and causing meningitis or meningoencephalitis …

During tumour progression, organelle function undergoes dramatic changes, and crosstalk
among organelles plays a significant role. Crosstalk between mitochondria and other …

Mitochondria are essential double-membrane organelles with intricate structures and
diverse functions within cells. Under normal physiological conditions, mitochondria regulate …