Leptospira: the dawn of the molecular genetics era for an emerging zoonotic pathogen
Leptospirosis is a zoonotic disease that has emerged as an important cause of morbidity
and mortality among impoverished populations. One hundred years after the discovery of …
and mortality among impoverished populations. One hundred years after the discovery of …
Leptospira as an Emerging Pathogen: A Review of its Biology, Pathogenesis and Host Immune Responses
KV Evangelista, J Coburn - Future microbiology, 2010 - Taylor & Francis
Leptospirosis, the most widespread zoonosis in the world, is an emerging public health
problem, particularly in large urban centers of develo** countries. Several pathogenic …
problem, particularly in large urban centers of develo** countries. Several pathogenic …
What Makes a Bacterial Species Pathogenic?:Comparative Genomic Analysis of the Genus Leptospira
Leptospirosis, caused by spirochetes of the genus Leptospira, is a globally widespread,
neglected and emerging zoonotic disease. While whole genome analysis of individual …
neglected and emerging zoonotic disease. While whole genome analysis of individual …
Complement control protein factor H: the good, the bad, and the inadequate
The complement system is an essential component of the innate immune system that
participates in elimination of pathogens and altered host cells and comprises an essential …
participates in elimination of pathogens and altered host cells and comprises an essential …
Leptospiral infection, pathogenesis and its diagnosis—A review
Leptospirosis is a perplexing conundrum for many. In the existing literature, the
pathophysiological mechanisms pertaining to leptospirosis is still not understood in full …
pathophysiological mechanisms pertaining to leptospirosis is still not understood in full …
Fibronectin: a multidomain host adhesin targeted by bacterial fibronectin-binding proteins
B Henderson, S Nair, J Pallas… - FEMS microbiology …, 2011 - academic.oup.com
Fibronectin, a large and essential multidomain glycoprotein, with multiple adhesive
properties, functioning as a key link between cells and their extracellular matrices, is now …
properties, functioning as a key link between cells and their extracellular matrices, is now …
Hijacking factor H for complement immune evasion
The complement system is an essential player in innate and adaptive immunity. It consists of
three pathways (alternative, classical, and lectin) that initiate either spontaneously …
three pathways (alternative, classical, and lectin) that initiate either spontaneously …
[HTML][HTML] Complement factor H related proteins (CFHRs)
C Skerka, Q Chen, V Fremeaux-Bacchi… - Molecular …, 2013 - Elsevier
Factor H related proteins comprise a group of five plasma proteins: CFHR1, CFHR2,
CFHR3, CFHR4 and CFHR5, and each member of this group binds to the central …
CFHR3, CFHR4 and CFHR5, and each member of this group binds to the central …
Genome reduction in Leptospira borgpetersenii reflects limited transmission potential
DM Bulach, RL Zuerner, P Wilson… - Proceedings of the …, 2006 - National Acad Sciences
Leptospirosis is one of the most common zoonotic diseases in the world, resulting in high
morbidity and mortality in humans and affecting global livestock production. Most infections …
morbidity and mortality in humans and affecting global livestock production. Most infections …
Genome Sequence of the Saprophyte Leptospira biflexa Provides Insights into the Evolution of Leptospira and the Pathogenesis of Leptospirosis
M Picardeau, DM Bulach, C Bouchier, RL Zuerner… - PloS one, 2008 - journals.plos.org
Leptospira biflexa is a free-living saprophytic spirochete present in aquatic environments.
We determined the genome sequence of L. biflexa, making it the first saprophytic Leptospira …
We determined the genome sequence of L. biflexa, making it the first saprophytic Leptospira …