Prevalence of comorbid substance use in schizophrenia spectrum disorders in community and clinical settings, 1990–2017: Systematic review and meta-analysis

GE Hunt, MM Large, M Cleary, HMX Lai… - Drug and alcohol …, 2018 - Elsevier
Background Comorbidity is highly prevalent between substance use disorders (SUDs) and
schizophrenia. This systematic review and meta-analysis estimated prevalence rates of …

The link between schizophrenia and substance use disorder: A unifying hypothesis

JY Khokhar, LL Dwiel, AM Henricks, WT Doucette… - Schizophrenia …, 2018 - Elsevier
Substance use disorders occur commonly in patients with schizophrenia and dramatically
worsen their overall clinical course. While the exact mechanisms contributing to substance …

Continued versus discontinued cannabis use in patients with psychosis: a systematic review and meta-analysis

T Schoeler, A Monk, MB Sami, E Klamerus… - The Lancet …, 2016 - thelancet.com
Background Although the link between cannabis use and development of psychosis is well
established, less is known about the effect of continued versus discontinued cannabis use …

Cannabis and the brain

L Iversen - Brain, 2003 - academic.oup.com
The active compound in herbal cannabis, Δ9‐tetrahydrocannabinol, exerts all of its known
central effects through the CB1 cannabinoid receptor. Research on cannabinoid …

Delta-9-tetrahydrocannabinol effects in schizophrenia: implications for cognition, psychosis, and addiction

DC D'Souza, WM Abi-Saab, S Madonick… - Biological …, 2005 - Elsevier
BACKGROUND: Recent advances in the neurobiology of cannabinoids have renewed
interest in the association between cannabis and psychotic disorders. METHODS: In a 3 …

Cannabis abuse and the course of recent-onset schizophrenic disorders

DH Linszen, PM Dingemans… - Archives of general …, 1994 - jamanetwork.com
Objective: We sought to examine the relation between cannabis abuse and the symptomatic
course of recent-onset schizophrenia and related disorders. Design: A prospective cohort …

[LLIBRE][B] The science of marijuana

LL Iversen - 2001 - books.google.com
After alcohol and nicotine, marijuana is the most commonly used" recreational" drug in
Western countries. There has already been a growing debate about the medical …

Unique effects of clozapine: a pharmacological perspective

JY Khokhar, AM Henricks, EDK Sullivan… - Advances in …, 2018 - Elsevier
Schizophrenia is a heterogenous and severe neuropsychiatric disorder that affects nearly
1% of the population worldwide. Antipsychotic drugs are the mainstay of treatment, but not …

Psychiatric effects of cannabis

A Johns - The British Journal of Psychiatry, 2001 - cambridge.org
BackgroundCannabis is commonly regarded as an innocuous drug and the prevalence of
lifetime and regular use has increased in most developed countries. However, accumulative …

Cannabis and psychosis/schizophrenia: human studies

DC D'Souza, RA Sewell, M Ranganathan - European archives of …, 2009 - Springer
The association between cannabis use and psychosis has long been recognized. Recent
advances in knowledge about cannabinoid receptor function have renewed interest in this …