The widespread regulation of microRNA biogenesis, function and decay
J Krol, I Loedige, W Filipowicz - Nature reviews genetics, 2010 - nature.com
MicroRNAs (miRNAs) are a large family of post-transcriptional regulators of gene expression
that are∼ 21 nucleotides in length and control many developmental and cellular processes …
that are∼ 21 nucleotides in length and control many developmental and cellular processes …
BDNF-induced local protein synthesis and synaptic plasticity
G Leal, D Comprido, CB Duarte - Neuropharmacology, 2014 - Elsevier
Brain-derived neurotrophic factor (BDNF) is an important regulator of synaptic transmission
and long-term potentiation (LTP) in the hippocampus and in other brain regions, playing a …
and long-term potentiation (LTP) in the hippocampus and in other brain regions, playing a …
P-body purification reveals the condensation of repressed mRNA regulons
A Hubstenberger, M Courel, M Bénard, S Souquere… - Molecular cell, 2017 - cell.com
Within cells, soluble RNPs can switch states to coassemble and condense into liquid or solid
bodies. Although these phase transitions have been reconstituted in vitro, for endogenous …
bodies. Although these phase transitions have been reconstituted in vitro, for endogenous …
RNA granules: post-transcriptional and epigenetic modulators of gene expression
P Anderson, N Kedersha - Nature reviews Molecular cell biology, 2009 - nature.com
The composition of cytoplasmic messenger ribonucleoproteins (mRNPs) is determined by
their nuclear and cytoplasmic histories and reflects past functions and future fates. The …
their nuclear and cytoplasmic histories and reflects past functions and future fates. The …
RNA transport and local translation in neurodevelopmental and neurodegenerative disease
MS Fernandopulle, J Lippincott-Schwartz… - Nature …, 2021 - nature.com
Neurons decentralize protein synthesis from the cell body to support the active metabolism
of remote dendritic and axonal compartments. The neuronal RNA transport apparatus …
of remote dendritic and axonal compartments. The neuronal RNA transport apparatus …
mRNP granules: assembly, function, and connections with disease
JR Buchan - RNA biology, 2014 - Taylor & Francis
Messenger ribonucleoprotein (mRNP) granules are dynamic, self-assembling structures that
harbor non-translating mRNAs bound by various proteins that regulate mRNA translation …
harbor non-translating mRNAs bound by various proteins that regulate mRNA translation …
RNA-binding proteins balance brain function in health and disease
Posttranscriptional gene expression including splicing, RNA transport, translation, and RNA
decay provides an important regulatory layer in many if not all molecular pathways …
decay provides an important regulatory layer in many if not all molecular pathways …
New insights into the role of brain-derived neurotrophic factor in synaptic plasticity
EG Waterhouse, B Xu - Molecular and Cellular Neuroscience, 2009 - Elsevier
Substantial evidence indicates that brain-derived neurotrophic factor (BDNF) plays a crucial
role in synaptic plasticity. Long-lasting synaptic plasticity is restricted to active synapses and …
role in synaptic plasticity. Long-lasting synaptic plasticity is restricted to active synapses and …
Translational control of localized mRNAs: restricting protein synthesis in space and time
As highlighted by recent genome-wide analyses in diverse organisms and cell types,
subcellular targeting of mRNAs has emerged as a major mechanism for cells to establish …
subcellular targeting of mRNAs has emerged as a major mechanism for cells to establish …
RNA granules: the good, the bad and the ugly
MG Thomas, M Loschi, MA Desbats, GL Boccaccio - Cellular signalling, 2011 - Elsevier
Processing bodies (PBs) and Stress Granules (SGs) are the founding members of a new
class of RNA granules, known as mRNA silencing foci, as they harbour transcripts …
class of RNA granules, known as mRNA silencing foci, as they harbour transcripts …