Protein glycosylation involves the co-translational or post-translational addition of glycans to
proteins and is a crucial protein modification in health and disease. The aim of …

Abstract Coronavirus disease 2019 (COVID-19), a highly infectious disease caused by
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has infected more than …

Glycosylation is a prevalent, yet heterogeneous modification with a broad range of
implications in molecular biology. This heterogeneity precludes enrichment strategies that …

Sialic acids, a subset of nine carbon acidic sugars, often exist as the terminal sugars of
glycans on either glycoproteins or glycolipids on the cell surface. Sialic acids play important …

The biological compositions including cells, proteins/peptides, nucleic acids, extracellular
vesicles (EVs) and metabolites are no doubt closely related to almost all physiological and …

Mass spectrometry–based glycoproteomics has gone through some incredible
developments over the last few years. Technological advances in glycopeptide enrichment …

Glycosylation is one of the most significant and abundant posttranslational modifications in
mammalian cells. It mediates a wide range of biofunctions, including cell adhesion, cell …

Protein glycosylation plays a critical and non-negligible role in many biological processes,
and some glycosylated proteins are important biomarkers. However, the identification and …

Protein glycosylation is one of the most common post-translational modifications that are
essential for cell function across all domains of life. Changes in glycosylation are considered …

Owing to the formidable challenge posed by microheterogeneities in glycosylation sites,
macroheterogeneity of the modification number of glycans, and low abundance and …