During the cancerous transformation of normal hepatocytes into hepatocellular carcinoma
(HCC), the enzyme catalyzing the first rate-limiting step of glycolysis, namely the …

Background Genome-wide association studies (GWASs) have identified some immune-
related single-nucleotide polymorphisms (SNPs) to be associated with leprosy. Methods …

Growth traits are critical economic traits in sheep. Genetic polymorphism has a great
influence on the improvement of sheep traits. The aim of this study was to analyze the effect …

Purpose Genome-wide association studies (GWAS) have identified multiple genetic variants
associated with leprosy. To investigate the single and combined associations between …

Algorithmic methods for interpreting the collective transcriptome (gene expression) patterns
of disease cohorts in the context of biological networks are a cornerstone of systems …

Identifying genetic determinants for longitudinal changes in albumin excretion in individuals
with type 1 diabetes may help identify those that are predisposed to renal, retinal and …

Hexokinases catalyze the first step of glycolysis by phosphorylating glucose. In the liver,
normal hepatocytes express the low-affinity hexokinase 4, also known as glucokinase …