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The schizophrenia syndrome, circa 2024: What we know and how that informs its nature
R Tandon, H Nasrallah, S Akbarian… - Schizophrenia …, 2024 - Elsevier
With new data about different aspects of schizophrenia being continually generated, it
becomes necessary to periodically revisit exactly what we know. Along with a need to review …
becomes necessary to periodically revisit exactly what we know. Along with a need to review …
On the origins of schizophrenia
RS Kahn - American Journal of Psychiatry, 2020 - psychiatryonline.org
What have we accomplished for schizophrenia patients since the introduction of
chlorpromazine in 1952 (1)? Have we really made a difference in the outcome of …
chlorpromazine in 1952 (1)? Have we really made a difference in the outcome of …
Cognitive impairment in schizophrenia: relationships with cortical thickness in fronto-temporal regions, and dissociability from symptom severity
Cognitive impairments are a core and persistent characteristic of schizophrenia with
implications for daily functioning. These show only limited response to antipsychotic …
implications for daily functioning. These show only limited response to antipsychotic …
Genome-wide association studies of schizophrenia and bipolar disorder in a diverse cohort of US veterans
Background Schizophrenia (SCZ) and bipolar disorder (BIP) are debilitating
neuropsychiatric disorders, collectively affecting 2% of the world's population. Recognizing …
neuropsychiatric disorders, collectively affecting 2% of the world's population. Recognizing …
Accuracy of immediate self-assessment of neurocognitive test performance: associations with psychiatric diagnosis and longitudinal psychotic symptoms
Participants with schizophrenia (SCZ) and bipolar disorder (BD) have challenges in self-
evaluation of their cognitive and functional abilities, referred to as introspective accuracy …
evaluation of their cognitive and functional abilities, referred to as introspective accuracy …
Cross-diagnostic determinants of cognitive functioning: the muscarinic cholinergic receptor as a model system
Cognitive impairment is a predictor of disability across different neuropsychiatric conditions,
and cognitive abilities are also strongly related to educational attainment and indices of life …
and cognitive abilities are also strongly related to educational attainment and indices of life …
Genome-wide association study accounting for anticholinergic burden to examine cognitive dysfunction in psychotic disorders
S Eum, SK Hill, N Alliey-Rodriguez… - …, 2021 - nature.com
Identifying genetic contributors to cognitive impairments in psychosis-spectrum disorders
can advance understanding of disease pathophysiology. Although CNS medications are …
can advance understanding of disease pathophysiology. Although CNS medications are …
[HTML][HTML] Neurocognitive variability in schizophrenia spectrum disorders: relationship to real-world functioning
L Helldin, C Mohn, AK Olsson, F Hjärthag - Schizophrenia Research …, 2020 - Elsevier
Neurocognitive variability exists within the schizophrenia spectrum disorder (SSD)
population, with subgroups performing at the same level as healthy samples Here we study …
population, with subgroups performing at the same level as healthy samples Here we study …
Imputed expression of schizophrenia‐associated genes and cognitive measures in patients with schizophrenia
Background Cognitive dysfunction is a core manifestation of schizophrenia and one of the
best predictors of long‐term disability. Genes increasing risk for schizophrenia may partly act …
best predictors of long‐term disability. Genes increasing risk for schizophrenia may partly act …
Factor structure of cognitive performance and functional capacity in schizophrenia: evidence for differences across functional capacity measures
Background Cognition and functional capacity predict functional outcomes in mental illness.
Traditional approaches conceptualize cognition as comprised of domains, but many studies …
Traditional approaches conceptualize cognition as comprised of domains, but many studies …