The global burden of sepsis: barriers and potential solutions

KE Rudd, N Kissoon, D Limmathurotsakul, S Bory… - Critical care, 2018 - Springer
Sepsis is a major contributor to the global burden of disease. The majority of sepsis cases
and deaths are estimated to occur in low and middle-income countries. Barriers to reducing …

The burden and contemporary epidemiology of sepsis in children

RS Watson, ED Carrol, MJ Carter… - The Lancet Child & …, 2024 - thelancet.com
Sepsis is a dysregulated host response to infection that leads to life-threatening organ
dysfunction. Half of the 50 million people affected by sepsis globally every year are …

Childhood mortality during and after acute illness in Africa and south Asia: a prospective cohort study

AH Diallo, ASMSB Shahid, AF Khan… - The Lancet Global …, 2022 - thelancet.com
Background Mortality among children with acute illness in low-income and middle-income
settings remains unacceptably high and the importance of post-discharge mortality is …

Post-discharge morbidity and mortality in children admitted with severe anaemia and other health conditions in malaria-endemic settings in Africa: a systematic review …

TK Kwambai, AT Mori, S Nevitt, AM van Eijk… - The Lancet Child & …, 2022 - thelancet.com
Background Severe anaemia is associated with high in-hospital mortality among young
children. In malaria-endemic areas, surviving children also remain at increased risk of …

Predictors of mortality in neonates and infants hospitalized with sepsis or serious infections in develo** countries: a systematic review

L Liang, N Kotadia, L English, N Kissoon… - Frontiers in …, 2018 - frontiersin.org
Background: Neonates and infants comprise the majority of the 6 million annual deaths
under 5 years of age around the world. Most of these deaths occur in low/middle income …

Paediatric postdischarge mortality in develo** countries: a systematic review

B Nemetchek, L English, N Kissoon, JM Ansermino… - BMJ open, 2018 - bmjopen.bmj.com
Objectives To update the current evidence base on paediatric postdischarge mortality (PDM)
in develo** countries. Secondary objectives included an evaluation of risk factors, timing …

[HTML][HTML] Pediatric post-discharge mortality in resource-poor countries: a systematic review and meta-analysis

M Knappett, V Nguyen, M Chaudhry, J Trawin… - …, 2024 - thelancet.com
Background Under-five mortality remains concentrated in resource-poor countries. Post-
discharge mortality is becoming increasingly recognized as a significant contributor to …

Mortality after inpatient treatment for severe pneumonia in children: a cohort study

MM Ngari, G Fegan, MK Mwangome… - Paediatric and …, 2017 - Wiley Online Library
Background Although pneumonia is a leading cause of inpatient mortality, deaths may also
occur after discharge from hospital. However, prior studies have been small, in selected …

Biomarkers of post-discharge mortality among children with complicated severe acute malnutrition

JM Njunge, A Gwela, NK Kibinge, M Ngari… - Scientific reports, 2019 - nature.com
High mortality after discharge from hospital following acute illness has been observed
among children with Severe Acute Malnutrition (SAM). However, mechanisms that may be …

[HTML][HTML] Risk factors for postdischarge mortality following hospitalization for severe acute malnutrition in Zimbabwe and Zambia

M Bwakura-Dangarembizi, C Dumbura, B Amadi… - The American journal of …, 2021 - Elsevier
Background Children discharged from hospital following management of complicated
severe acute malnutrition (SAM) have a high risk of mortality, especially HIV-positive …