Aqueous solubility is one of the major challenges in the early stages of drug discovery. One
of the most common and effective methods for enhancing solubility is the addition of an …

This study aimed to improve the pH-independent solubility and dissolution characteristics of
valsartan via the preparation of solid dispersions (SD) with poloxamer 407. SDs was …

To develop a valsartan-loaded gelatin microcapsule using hydroxypropylmethylcellulose
(HPMC) as a stabilizer, which could improve the physical stability and bioavailability of …

The poor aqueous solubility of drugs is a challenging problem faced by pharmaceutical
scientists in drug formulation. Cosolvency and micellization techniques have been severally …

Valsartan (VAL) is a potent, highly selective and orally active antihypertensive drug and is
poorly soluble in aqueous fluids, especially in gastric fluids, and its absorption is thus …

Lamotrigine, an antiepileptic agent belonging to class II of the Biopharmaceutical
Classification System (BCS), has linear pharmacokinetics and wide therapeutic window thus …

Introduction: Flash tablet is one of the newer technologies that recently have been focused
on. flash tablet offers many advantages such as fast disintegration and dissolution. However …

The very poor aqueous solubility of drugs, give rise to difficulties in the design of
pharmaceutical formulations and very often lead to variable oral bioavailability. Cosolvency …

The present investigation includes the preparation of liquid filling formulations for soft gels
using an antihypertensive drug, valsartan (VAL), in order to improve its dissolution …

The oral drug delivery is the most generally used route of administration that has been
explored for the delivery of drugs through various pharmaceutical products. Solubility of drug …