Sodium-glucose cotransporter 2 inhibitors and cancer: a systematic review and meta-analysis
B Xu, B Kang, S Li, S Fan, J Zhou - Journal of Endocrinological …, 2024 - Springer
Background The effect of sodium–glucose cotransporter 2 (SGLT2) inhibitors on cancer has
yet to be fully elucidated. Objective This systematic review and meta-analysis investigated …
yet to be fully elucidated. Objective This systematic review and meta-analysis investigated …
Pharmacological targets of SGLT2 inhibition on prostate cancer mediated by circulating metabolites: A drug-target Mendelian randomization study
Y Lin, Y Zhang, S Wang, L Cao, R Zhao, X Ma… - Frontiers in …, 2024 - frontiersin.org
Background The relationship between sodium-glucose cotransporter 2 (SGLT2) inhibitors
and prostate cancer is still unknown. Although these inhibitors can influence tumor …
and prostate cancer is still unknown. Although these inhibitors can influence tumor …
Revisiting the association between sodium-glucose cotransporter-2 inhibitors and the risk of neoplasm in patients with type 2 diabetes: new insights from an updated …
Y Wang, Z Li, C Lin, X Cai, F Lv… - Expert Review of …, 2025 - Taylor & Francis
Objective To evaluate the association between sodium-glucose cotransporter-2 inhibitors
(SGLT-2i) and the risk of neoplasm in patients with Type 2 diabetes (T2D). Methods …
(SGLT-2i) and the risk of neoplasm in patients with Type 2 diabetes (T2D). Methods …
SGLT2 inhibition and three urological cancers: Up‐to‐date results
L Lin, K Ning, L **ang, L Peng… - … /Metabolism Research and …, 2024 - Wiley Online Library
Objective To identify the causal role of sodium‐glucose cotransporter 2 (SGLT2) inhibition
on three urological cancers. Methods Six single nucleotide polymorphisms associated with …
on three urological cancers. Methods Six single nucleotide polymorphisms associated with …
SGLT2 inhibitor promotes mitochondrial dysfunction and ER-phagy in colorectal cancer cells
C Anastasio, I Donisi, V Del Vecchio, A Colloca… - Cellular & Molecular …, 2024 - Springer
Background Sodium-glucose transporter 2 (SGLT2) inhibitors (iSGLT2) are approved
medications for type 2 diabetes. Recent studies indicate that iSGLT2 inhibit the growth of …
medications for type 2 diabetes. Recent studies indicate that iSGLT2 inhibit the growth of …
Liraglutide promotes UCP1 expression and lipolysis of adipocytes by promoting the secretion of irisin from skeletal muscle cells
N Zhang, H Zhou, Y Xu, Y Zhang, F Yu, L Gui… - Molecular and Cellular …, 2024 - Elsevier
Abstract Although Liraglutide (Lira) increases serum irisin levels in type 2 diabetes mellitus
(T2DM), it is unclear whether it induces expression of uncoupling protein 1 (UCP1) of …
(T2DM), it is unclear whether it induces expression of uncoupling protein 1 (UCP1) of …
Exploring the role and application of mitochondria in radiation therapy
Y Ding, W **g, Z Kang, Z Yang - … et Biophysica Acta (BBA)-Molecular Basis …, 2024 - Elsevier
Mitochondria are pivotal in cellular energy metabolism, the oxidative stress response and
apoptosis. Recent research has focused on harnessing their functions to enhance the …
apoptosis. Recent research has focused on harnessing their functions to enhance the …
Risks and Benefits of SGLT-2 Inhibitors for Type 1 Diabetes Patients Using Automated Insulin Delivery Systems—A Literature Review
The primary treatment for autoimmune Diabetes Mellitus (Type 1 Diabetes Mellitus-T1DM) is
insulin therapy. Unfortunately, a multitude of clinical cases has demonstrated that the use of …
insulin therapy. Unfortunately, a multitude of clinical cases has demonstrated that the use of …
Growth differentiation factor 15 (GDF15) predicts relapse free and overall survival in unresected locally advanced non-small cell lung cancer treated with …
F Di Pastena, G Pond, EE Tsakiridis, A Gouveia… - Radiation …, 2024 - Springer
Introduction Growth differentiation factor 15 (GDF15) is a cytokine of the TGFβ family. Here,
we analyzed GDF15 levels in patients with locally advanced non-small cell lung cancer (LA …
we analyzed GDF15 levels in patients with locally advanced non-small cell lung cancer (LA …
Envisioning Glucose Transporters (GLUTs and SGLTs) as Novel Intervention against Cancer: Drug Discovery Perspective and Targeting Approach
Metabolic reprogramming and altered cellular energetics have been recently established as
an important cancer hallmark. The modulation of glucose metabolism is one of the important …
an important cancer hallmark. The modulation of glucose metabolism is one of the important …