Biologics such as monoclonal antibodies are much more complex than small-molecule
drugs, which raises challenging questions for the development and regulatory evaluation of …

In this contribution the use of Analytical Ultracentrifugation (AUC) for the modern analysis of
colloids is reviewed. Since AUC is a fractionation technique, distributions of the …

The worldwide trend in nanoparticle technology toward increasing complexity must be
directly linked to more advanced characterization methods of size, shape and related …

The current status of the UltraScan-III (US3) data analysis software suite is described. An
overview of the US3 concepts, software layout, the data workflows and US3 components is …

Analytical ultracentrifugation experiments play an integral role in the solution phase
characterization of recombinant proteins and other biological macromolecules. This unit …

This work highlights significant advancements in detector hardware and software for
multiwavelength analytical ultracentrifugation (MWL-AUC) experiments, demonstrating …

Granulometry is the regulatory category where the differences between traditional materials
and nanomaterials culminate. Reported herein is a careful validation of methods for the …

The incorporation of nanomaterials into products can improve performance, efficiency, and
durability in various fields ranging from construction, energy management, catalysis …

The analytical ultracentrifuge (AUC) and the modern field of analytical ultracentrifugation
found its inception approximately a century ago. We highlight the scope of its major …

We demonstrate how a sophisticated data analysis methodology enables us to perform
multiwavelength evaluations of dynamic rotor speed gradient experiments obtained by …