Breaking bad: how viruses subvert the cell cycle

Y Fan, S Sanyal, R Bruzzone - Frontiers in cellular and infection …, 2018 - frontiersin.org
Interactions between the host and viruses during the course of their co-evolution have not
only shaped cellular function and the immune system, but also the counter measures …

Cell cycle regulation during viral infection

S Bagga, MJ Bouchard - Cell Cycle Control: Mechanisms and Protocols, 2014 - Springer
To replicate their genomes in cells and generate new progeny, viruses typically require
factors provided by the cells that they have infected. Subversion of the cellular machinery …

The SARS Coronavirus 3a protein causes endoplasmic reticulum stress and induces ligand-independent downregulation of the type 1 interferon receptor

R Minakshi, K Padhan, M Rani, N Khan, F Ahmad… - PloS one, 2009 - journals.plos.org
The Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) is reported to cause
apoptosis of infected cells and several of its proteins including the 3a accessory protein, are …

Cyclin-dependent kinases as emerging targets for develo** novel antiviral therapeutics

L Gutierrez-Chamorro, E Felip, IJ Ezeonwumelu… - Trends in …, 2021 - cell.com
Besides its prominent role in cell proliferation, cyclin-dependent kinases (CDKs) are key
players in viral infections as both DNA and RNA viruses modify CDK function to favor viral …

The hepatitis B virus interactome: a comprehensive overview

E Van Damme, J Vanhove, B Severyn… - Frontiers in …, 2021 - frontiersin.org
Despite the availability of a prophylactic vaccine, chronic hepatitis B (CHB) caused by the
hepatitis B virus (HBV) is a major health problem affecting an estimated 292 million people …

Pharmacoinformatics Analysis Reveals Flavonoids and Diterpenoids from Andrographis paniculata and Thespesia populnea to Target Hepatocellular Carcinoma …

VS Patil, DR Harish, U Vetrivel, SH Deshpande… - Applied Sciences, 2022 - mdpi.com
Herbs are widely utilized in the Western Ghats region of India to treat liver diseases and viral-
like infections. However, such practices lack scientific evidence at the molecular level and …

The hepatitis B virus X protein modulates hepatocyte proliferation pathways to stimulate viral replication

TL Gearhart, MJ Bouchard - Journal of virology, 2010 - Am Soc Microbiol
Worldwide, there are over 350 million people who are chronically infected with the human
hepatitis B virus (HBV); chronic HBV infections are associated with the development of …

Viral manipulation of DNA repair and cell cycle checkpoints

MS Chaurushiya, MD Weitzman - DNA repair, 2009 - Elsevier
Recognition and repair of DNA damage is critical for maintaining genomic integrity and
suppressing tumorigenesis. In eukaryotic cells, the sensing and repair of DNA damage are …

Chemopreventive and anti-cancer properties of the aqueous extract of flowers of Butea monosperma

T Choedon, SK Shukla, V Kumar - Journal of ethnopharmacology, 2010 - Elsevier
ETHNOPHARMACOLOGICAL RELEVANCE: Butea monosperma (Lam.)(Fabaceae)
popularly known as 'flame of the forest'has been widely used in the traditional Indian …

Cyclin-dependent kinase 2 phosphorylates s/tp sites in the hepadnavirus core protein C-terminal domain and is incorporated into viral capsids

L Ludgate, X Ning, DH Nguyen, C Adams… - Journal of …, 2012 - Am Soc Microbiol
Phosphorylation of the hepadnavirus core protein C-terminal domain (CTD) is important for
viral RNA packaging, reverse transcription, and subcellular localization. Hepadnavirus …