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Liquid biopsy approaches to capture tumor evolution and clinical outcomes during cancer immunotherapy
L Sivapalan, JC Murray… - Journal for …, 2023 - pmc.ncbi.nlm.nih.gov
Circulating cell-free tumor DNA (ctDNA) can serve as a real-time biomarker of tumor burden
and provide unique insights into the evolving molecular landscape of cancers under the …
and provide unique insights into the evolving molecular landscape of cancers under the …
Integrating circulating-free DNA (cfDNA) analysis into clinical practice: opportunities and challenges
In the current era of precision medicine, the identification of genomic alterations has
revolutionised the management of patients with solid tumours. Recent advances in the …
revolutionised the management of patients with solid tumours. Recent advances in the …
White blood cell and cell-free DNA analyses for detection of residual disease in gastric cancer
A Leal, NCT van Grieken, DN Palsgrove… - Nature …, 2020 - nature.com
Liquid biopsies are providing new opportunities for detection of residual disease in cell-free
DNA (cfDNA) after surgery but may be confounded through identification of alterations …
DNA (cfDNA) after surgery but may be confounded through identification of alterations …
Early plasma circulating tumor DNA (ctDNA) changes predict response to first-line pembrolizumab-based therapy in non-small cell lung cancer (NSCLC)
Background Currently available biomarkers are imperfect in their ability to predict responses
to the multiple first-line treatment options available for patients with advanced non-small cell …
to the multiple first-line treatment options available for patients with advanced non-small cell …
Deep sequencing of circulating tumor DNA detects molecular residual disease and predicts recurrence in gastric cancer
Identifying locoregional gastric cancer patients who are at high risk for relapse after
resection could facilitate early intervention. By detecting molecular residual disease (MRD) …
resection could facilitate early intervention. By detecting molecular residual disease (MRD) …
Liquid biopsy in the clinical management of hepatocellular carcinoma
With increasing knowledge on molecular tumour information, precision oncology has
revolutionised the medical field over the past years. Liquid biopsy entails the analysis of …
revolutionised the medical field over the past years. Liquid biopsy entails the analysis of …
[HTML][HTML] The liquid biopsy for lung cancer: state of the art, limitations and future developments
D Di Capua, D Bracken-Clarke, K Ronan, AM Baird… - Cancers, 2021 - mdpi.com
Simple Summary During the development and progression of lung tumors, processes such
as necrosis and vascular invasion shed tumor cells or cellular components into various fluid …
as necrosis and vascular invasion shed tumor cells or cellular components into various fluid …
Current and future applications of liquid biopsy in nonsmall cell lung cancer from early to advanced stages
N Guibert, A Pradines, G Favre… - European Respiratory …, 2020 - publications.ersnet.org
Liquid biopsy refers to the analysis of any tumour-derived material circulating in the blood or
any other body fluid. This concept is particularly relevant in lung cancer as the tumour is …
any other body fluid. This concept is particularly relevant in lung cancer as the tumour is …
[HTML][HTML] Biomarkers and lung cancer early detection: state of the art
Simple Summary Lung cancer is the leading cause of cancer death worldwide. Detecting
lung malignancies promptly is essential for any anticancer treatment to reduce mortality and …
lung malignancies promptly is essential for any anticancer treatment to reduce mortality and …
Genetics of hepatocellular carcinoma: from tumor to circulating DNA
Simple Summary In recent years, the genetic landscape of hepatocellular carcinoma (HCC)
has been explored, identifying TERT promoter, CTNNB1, and TP53 as the most frequent …
has been explored, identifying TERT promoter, CTNNB1, and TP53 as the most frequent …