Natural products and their structural analogues have historically made a major contribution
to pharmacotherapy, especially for cancer and infectious diseases. Nevertheless, natural …

Microbial secondary metabolites (MSMs) have played and continue to play a highly
significant role in the drug discovery and development process. Genetically, MSM chemical …

Natural product libraries contain specialized metabolites derived from plants, animals, and
microorganisms that play a pivotal role in drug discovery due to their immense structural …

Endophytic fungi became an attractive source for the discovery of new leads, because of the
complexity and the structural diversity of their secondary metabolites. The genus Fusarium …

The complexity and structural diversity of the secondary metabolites produced by
endophytes make them an attractive source of natural products with novel structures that can …

Natural products have played significant roles as medicine and food throughout human
history. Here, we first provide a brief historical overview of natural products, their …

Aspergillus niger, one of the most common and important fungal species, is ubiquitous in
various environments. A. niger isolates possess a large number of cryptic biosynthetic gene …

Plant endophytes are microorganisms that live in healthy plant tissues in part or all of their
life history without causing obvious symptoms of infection in the host plants. Endophytes, a …

In the search for new crop protection microbial biocontrol agents, isolates from the genus
Streptomyces are commonly found with promising attributes. Streptomyces are natural soil …

Endophytic fungi are now recognized as sources of pharmacologically beneficial, novel
bioactive compounds. This study was carried out to evaluate antiproliferative and …