Interaction between microbiota and immunity in health and disease

D Zheng, T Liwinski, E Elinav - Cell research, 2020 - nature.com
The interplay between the commensal microbiota and the mammalian immune system
development and function includes multifold interactions in homeostasis and disease. The …

Human gut microbiota/microbiome in health and diseases: a review

EZ Gomaa - Antonie Van Leeuwenhoek, 2020 - Springer
The human gut microbiota has received considerable interest in the recent years and our
knowledge of the inhabitant species and their potential applications is increased particularly …

The microbiome and gut homeostasis

JY Lee, RM Tsolis, AJ Bäumler - Science, 2022 - science.org
Changes in the composition of the gut microbiota are associated with many human
diseases. So far, however, we have failed to define homeostasis or dysbiosis by the …

Gut microbiota from green tea polyphenol-dosed mice improves intestinal epithelial homeostasis and ameliorates experimental colitis

Z Wu, S Huang, T Li, N Li, D Han, B Zhang, ZZ Xu… - Microbiome, 2021 - Springer
Background Alteration of the gut microbiota may contribute to the development of
inflammatory bowel disease (IBD). Epigallocatechin-3-gallate (EGCG), a major bioactive …

The gut microbiota in inflammatory bowel disease

P Qiu, T Ishimoto, L Fu, J Zhang, Z Zhang… - Frontiers in cellular and …, 2022 - frontiersin.org
Epidemiological surveys indicate that the incidence of inflammatory bowel disease (IBD) is
increasing rapidly with the continuous growth of the economy. A large number of studies …

The gut microbiome: Relationships with disease and opportunities for therapy

J Durack, SV Lynch - Journal of experimental medicine, 2019 - rupress.org
Over the past decade, our view of human-associated microbes has expanded beyond that of
a few species toward an appreciation of the diverse and niche-specialized microbial …

Host–microbiota interactions in inflammatory bowel disease

R Caruso, BC Lo, G Núñez - Nature Reviews Immunology, 2020 - nature.com
The mammalian intestine is colonized by trillions of microorganisms that have co-evolved
with the host in a symbiotic relationship. The presence of large numbers of symbionts near …

Microbial genes and pathways in inflammatory bowel disease

M Schirmer, A Garner, H Vlamakis… - Nature Reviews …, 2019 - nature.com
Perturbations in the intestinal microbiome are implicated in inflammatory bowel disease
(IBD). Studies of treatment-naive patients have identified microbial taxa associated with …

Discovery and inhibition of an interspecies gut bacterial pathway for Levodopa metabolism

V Maini Rekdal, EN Bess, JE Bisanz, PJ Turnbaugh… - Science, 2019 - science.org
INTRODUCTION Parkinson's disease is a debilitating neurological condition affecting more
than 1% of the global population aged 60 and above. The primary medication used to treat …

The intermucosal connection between the mouth and gut in commensal pathobiont-driven colitis

S Kitamoto, H Nagao-Kitamoto, Y Jiao, MG Gillilland… - Cell, 2020 - cell.com
The precise mechanism by which oral infection contributes to the pathogenesis of extra-oral
diseases remains unclear. Here, we report that periodontal inflammation exacerbates gut …