Posterior vitreous detachment (PVD) is the consequence of changes in the macromolecular
structure of gel vitreous that result in liquefaction, concurrent with alterations in the …

The transparent vitreous body, which occupies about 80% of the eye's volume, is laden with
numerous enzymatic and non-enzymatic antioxidants that could protect the eye from …

Intravitreal injection of biodegradable nanoparticles (NP) holds promise for gene therapy
and drug delivery to the back of the eye. In some cases, including gene therapy, NP need to …

PURPOSE: To compare the state of the posterior vitreous in exudative age-related macular
degeneration (AMD) with eyes with nonexudative AMD and controls. DESIGN: Prospective …

Importance Vitreous floaters are common and can worsen visual quality. YAG vitreolysis is
an untested treatment for floaters. Objective To evaluate YAG laser vitreolysis vs sham …

Purpose.: To determine if the accommodative forward movements of the vitreous zonule and
lens equator occur in the human eye, as they do in the rhesus monkey eye; to investigate the …

Purpose Pharmacologic vitreolysis is a promising new therapy to improve vitreoretinal
surgery and, ultimately, prevent disease by mitigating the contribution of vitreous to …

Introduction Ophthalmic diseases of the retina are a significant cause of vision loss globally.
Despite much progress, there remains an unmet need for durable, long-acting treatment …

The term pharmacologic vitreolysis first appeared in the world's literature one decade ago in
the pages of the journal Retina. 1 The coining of this term formalized a new field and was …

IN 1976, DR ERNST WYNDER, FOUNDING PRESIDENT OF THE American Health
Foundation and founding editor of the journal Preventive Medicine, stated that “It should be …