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Cuproptosis: harnessing transition metal for cancer therapy
Transition metal elements, such as copper, play diverse and pivotal roles in oncology. They
act as constituents of metalloenzymes involved in cellular metabolism, function as signaling …
act as constituents of metalloenzymes involved in cellular metabolism, function as signaling …
Designing bioresponsive nanomaterials for intracellular self-assembly
Supramolecular assemblies are essential components of living organisms. Cellular
scaffolds, such as the cytoskeleton or the cell membrane, are formed via secondary …
scaffolds, such as the cytoskeleton or the cell membrane, are formed via secondary …
Fundamental mechanisms of regulated cell death and implications for heart disease
Twelve regulated cell death programs have been described. We review in detail the basic
biology of nine including death receptor-mediated apoptosis, death receptor-mediated …
biology of nine including death receptor-mediated apoptosis, death receptor-mediated …
Understanding apoptosis and apoptotic pathways targeted cancer therapeutics
R Jan - Advanced pharmaceutical bulletin, 2019 - pmc.ncbi.nlm.nih.gov
Various physiological processes involve appropriate tissue developmental process and
homeostasis-the pathogenesis of several diseases connected with deregulatory apoptosis …
homeostasis-the pathogenesis of several diseases connected with deregulatory apoptosis …
Mechanisms of biological effects of ionic liquids: from single cells to multicellular organisms
KS Egorova, AV Kibardin, AV Posvyatenko… - Chemical …, 2024 - ACS Publications
The review presents a detailed discussion of the evolving field studying interactions
between ionic liquids (ILs) and biological systems. Originating from molten salt electrolytes …
between ionic liquids (ILs) and biological systems. Originating from molten salt electrolytes …
Caspase-6 is a key regulator of innate immunity, inflammasome activation, and host defense
Caspases regulate cell death, immune responses, and homeostasis. Caspase-6 is
categorized as an executioner caspase but shows key differences from the other …
categorized as an executioner caspase but shows key differences from the other …
[HTML][HTML] Targeting apoptotic caspases in cancer
A Boice, L Bouchier-Hayes - … et Biophysica Acta (BBA)-Molecular Cell …, 2020 - Elsevier
Members of the caspase family of proteases play essential roles in the initiation and
execution of apoptosis. These caspases are divided into two groups: the initiator caspases …
execution of apoptosis. These caspases are divided into two groups: the initiator caspases …
[HTML][HTML] Cell death in the origin and treatment of cancer
A Strasser, DL Vaux - Molecular cell, 2020 - cell.com
Cell death, or, more specifically, cell suicide, is a process of fundamental importance to
human health. Throughout our lives, over a million cells are produced every second. When …
human health. Throughout our lives, over a million cells are produced every second. When …
A long way to go: caspase inhibitors in clinical use
S Dhani, Y Zhao, B Zhivotovsky - Cell death & disease, 2021 - nature.com
Caspases are an evolutionary conserved family of cysteine-dependent proteases that are
involved in many vital cellular processes including apoptosis, proliferation, differentiation …
involved in many vital cellular processes including apoptosis, proliferation, differentiation …
The TNF family of ligands and receptors: communication modules in the immune system and beyond
C Dostert, M Grusdat, E Letellier… - Physiological …, 2019 - journals.physiology.org
The tumor necrosis factor (TNF) and TNF receptor (TNFR) superfamilies (TNFSF/TNFRSF)
include 19 ligands and 29 receptors that play important roles in the modulation of cellular …
include 19 ligands and 29 receptors that play important roles in the modulation of cellular …