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Recent developments in the use of kinase inhibitors for management of viral infections
Kinases are a group of therapeutic targets involved in the progression of numerous
diseases, including cancer, rheumatoid arthritis, Alzheimer's disease, and viral infections …
diseases, including cancer, rheumatoid arthritis, Alzheimer's disease, and viral infections …
Status of antiviral therapeutics against rabies virus and related emerging lyssaviruses
V Du Pont, RK Plemper, MJ Schnell - Current opinion in virology, 2019 - Elsevier
Rabies virus (RABV) constitutes a major social and economic burden associated with 60
000 deaths annually worldwide. Although pre-exposure and post-exposure treatment …
000 deaths annually worldwide. Although pre-exposure and post-exposure treatment …
[HTML][HTML] Rabies Virus Regulates Inflammatory Response in BV-2 Cells through Activation of Myd88 and NF-κB Signaling Pathways via TLR7
Y **e, Y Chi, X Tao, P Yu, Q Liu, M Zhang… - International Journal of …, 2024 - mdpi.com
Rabies is a fatal neurological infectious disease caused by rabies virus (RABV), which
invades the central nervous system (CNS). RABV with varying virulence regulates …
invades the central nervous system (CNS). RABV with varying virulence regulates …
Reevaluation of the efficacy of favipiravir against rabies virus using in vivo imaging analysis
K Yamada, K Noguchi, K Kimitsuki, R Kaimori, N Saito… - Antiviral Research, 2019 - Elsevier
Rabies virus (RABV) is a highly neurotropic virus and the causative agent of rabies, an
encephalitis with an almost 100% case-fatality rate that remains incurable after the onset of …
encephalitis with an almost 100% case-fatality rate that remains incurable after the onset of …
[HTML][HTML] Assessing rabies vaccine protection against a novel lyssavirus, Kotalahti bat lyssavirus
Rabies is a fatal encephalitis caused by an important group of viruses within the Lyssavirus
genus. The prototype virus, rabies virus, is still the most commonly reported lyssavirus and …
genus. The prototype virus, rabies virus, is still the most commonly reported lyssavirus and …
A One Medicine Mission for an Effective Rabies Therapy
Despite the disease's long history, little progress has been made toward a treatment for
rabies. The prognosis for patient recovery remains dire. For any prospect of survival, patients …
rabies. The prognosis for patient recovery remains dire. For any prospect of survival, patients …
[HTML][HTML] Pyrimethamine inhibits rabies virus replication in vitro
S Rogée, F Larrous, D Jochmans, Y Ben-Khalifa… - Antiviral Research, 2019 - Elsevier
Rabies virus transmits from animals to humans and causes encephalitis. Every year more
than 15 million people receive a post exposure prophylaxis (PEP) treatment that is highly …
than 15 million people receive a post exposure prophylaxis (PEP) treatment that is highly …
Trying to treat the untreatable: experimental approaches to clear rabies virus infection from the CNS
Rabies virus causes an invariably fatal encephalitis following the onset of clinical disease.
Despite the availability of safe and effective vaccines, the clinical stages of rabies …
Despite the availability of safe and effective vaccines, the clinical stages of rabies …
[HTML][HTML] BCX4430 inhibits the replication of rabies virus by suppressing mTOR-dependent autophagy in vitro
Y **e, YL Chi, SQ Liu, WY Zhu - Virology, 2023 - Elsevier
Rabies is a fatal neurological infectious disease caused by rabies virus (RABV). However,
no effective anti-RABV drugs for treatment during the symptomatic phase are available. The …
no effective anti-RABV drugs for treatment during the symptomatic phase are available. The …
Dual role of toll-like receptor 7 in the pathogenesis of rabies virus in a mouse model
Z Luo, L Lv, Y Li, B Sui, Q Wu, Y Zhang, J Pei… - Journal of …, 2020 - journals.asm.org
Rabies, caused by rabies virus (RABV), is a fatal encephalitis in humans and other
mammals, which continues to present a public health threat in most parts of the world. Our …
mammals, which continues to present a public health threat in most parts of the world. Our …