Emerging COVID-19 variants and their impact on SARS-CoV-2 diagnosis, therapeutics and vaccines

Q Fernandes, VP Inchakalody, M Merhi… - Annals of …, 2022‏ - Taylor & Francis
The emergence of novel and evolving variants of SARS-CoV-2 has fostered the need for
change in the form of newer and more adaptive diagnostic methods for the detection of …

Progress of the COVID-19 vaccine effort: viruses, vaccines and variants versus efficacy, effectiveness and escape

JS Tregoning, KE Flight, SL Higham, Z Wang… - Nature reviews …, 2021‏ - nature.com
Where 2020 saw the development and testing of vaccines against severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) at an unprecedented pace, the first half of 2021 has …

Association between mRNA vaccination and COVID-19 hospitalization and disease severity

MW Tenforde, WH Self, K Adams, M Gaglani, AA Ginde… - Jama, 2021‏ - jamanetwork.com
Importance A comprehensive understanding of the benefits of COVID-19 vaccination
requires consideration of disease attenuation, determined as whether people who develop …

[HTML][HTML] Effectiveness of mRNA BNT162b2 COVID-19 vaccine up to 6 months in a large integrated health system in the USA: a retrospective cohort study

SY Tartof, JM Slezak, H Fischer, V Hong, BK Ackerson… - The Lancet, 2021‏ - thelancet.com
Background Vaccine effectiveness studies have not differentiated the effect of the delta (B.
1.617. 2) variant and potential waning immunity in observed reductions in effectiveness …

Waning of BNT162b2 vaccine protection against SARS-CoV-2 infection in Qatar

H Chemaitelly, P Tang, MR Hasan… - … England Journal of …, 2021‏ - Mass Medical Soc
Background Waning of vaccine protection against severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) infection or coronavirus disease 2019 (Covid-19) is a concern …

The efficacy and effectiveness of the COVID-19 vaccines in reducing infection, severity, hospitalization, and mortality: a systematic review

I Mohammed, A Nauman, P Paul… - Human vaccines & …, 2022‏ - Taylor & Francis
With the relatively rapid development of the COVID-19 pandemic, vaccine development has
become crucial for limiting disease transmission. The accelerated growth in the approved …

Protection against SARS-CoV-2 after Covid-19 vaccination and previous infection

V Hall, S Foulkes, F Insalata, P Kirwan… - … England Journal of …, 2022‏ - Mass Medical Soc
Background The duration and effectiveness of immunity from infection with and vaccination
against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are relevant to …

SARS-CoV-2 breakthrough infections in vaccinated individuals: measurement, causes and impact

M Lipsitch, F Krammer, G Regev-Yochay… - Nature Reviews …, 2022‏ - nature.com
Breakthrough infections with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-
2) in fully vaccinated individuals are receiving intense scrutiny because of their importance …

Effectiveness of Covid-19 vaccines against the B. 1.617. 2 (Delta) variant

J Lopez Bernal, N Andrews, C Gower… - … England Journal of …, 2021‏ - Mass Medical Soc
Abstract Background The B. 1.617. 2 (delta) variant of the severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), the virus that causes coronavirus disease 2019 (Covid-19) …

Effectiveness and safety of SARS-CoV-2 vaccine in real-world studies: a systematic review and meta-analysis

Q Liu, C Qin, M Liu, J Liu - Infectious diseases of poverty, 2021‏ - mednexus.org
Background: To date, coronavirus disease 2019 (COVID-19) becomes increasingly fierce
due to the emergence of variants. Rapid herd immunity through vaccination is needed to …