Investigating the reactivity and cellular interactions of indazole-based ruthenium (ii) complexes in cancer and leishmania cells

DKS Sales, GC Fernandes, CDS da Silva… - New Journal of …, 2024 - pubs.rsc.org
This research focused on the synthesis and analysis of two novel Ru (II)-based complexes,
cis-[RuCl (Hind)(phen) 2] PF6 (FOR022) and cis-[Ru (Hind) 2 (phen) 2](PF6) 2 (FOR0E2) …

A bis-indazolic ruthenium (II) complex: Reactivity and biological studies on cancer cells

DKS Sales, LMT Simplicio, CDS da Silva… - Inorganica Chimica …, 2021 - Elsevier
Ru (II)-based complexes have been widely investigated as potential anticancer agents,
leading cell death of tumor mass. In this work, a metal complex, cis-[Ru II (Hind) 2 (bpy) …

New nitroindazolylacetonitriles: Efficient synthetic access via vicarious nucleophilic substitution and tautomeric switching mediated by anions

M Eddahmi, NMM Moura, L Bouissane… - New Journal of …, 2019 - pubs.rsc.org
New N-alkyl-nitroindazolylacetonitriles were efficiently obtained via vicarious nucleophilic
substitution of N-methyl-nitroindazoles with 4-chlorophenoxyacetonitrile. All compounds …

[HTML][HTML] A multidisciplinary study of chemico-physical properties of different classes of 2-aryl-5 (or 6)-nitrobenzimidazoles: NMR, electrochemical behavior, ESR, and …

EM Rakib, C Boga, M Calvaresi, M Chigr… - Arabian Journal of …, 2021 - Elsevier
Continuing in our researches on the syntheses, reactivity, pharmacological/biological
activities of heterocyclic compounds containing one or more nitrogen atoms we have …

A suitable functionalization of nitroindazoles with triazolyl and pyrazolyl moieties via cycloaddition reactions

M Eddahmi, NMM Moura, L Bouissane, O Amiri… - Molecules, 2019 - mdpi.com
The alkylation of a series of nitroindazole derivatives with 1, 2-dibromoethane afforded the
corresponding N-(2-bromoethyl)-and N-vinyl-nitro-1 H-indazoles. The Cu (I)-catalysed azide …

[PDF][PDF] C3-indazole functionalization: a review

F Giraud, F Anizon, P Moreau - Targets in Heterocyclic System …, 2021 - soc.chim.it
Indazoles are versatile building blocks generating numerous in-depth studies for their
synthesis and regioselective functionalization. In this review, we focused on non-patent …

Reactivity in 7-benzyl-2, 7-naphthyridine derivatives: Nucleophilic substitutions, rearrangements, heterocyclizations and related reactions

SN Sirakanyan, VA Kartsev, D Spinelli… - Current Organic …, 2017 - ingentaconnect.com
Background and Objective: Continuing our studies in the field of a new rearrangement in the
2, 7-naphthyridine series, the synthesis and rearrangement of mono-2 and di-amino …

nitroindazole précurseur de synthèse de nouveaux systèmes hétérocycliques (indazoles polysubstituées et indazoles-porphyrines) à visée thérapeutique

E MOHAMMED - 2020 - toubkal.imist.ma
Les travaux de recherche sur l'indazole sont largement multipliés aussi bien sur le plan
chimique portant sur le développement et l'optimisation de nouvelles voies de synthèse …

reduction des nitroheteroaryles: synthese, etude biologique et electrochimique de nouveaux systemes heterocycliques

M EL-GHOZLANI - 2018 - toubkal.imist.ma
L'indazole et ses dérivés ont gagné une importance considérable dans la chimie médicinale
grâce à leurs propriétés pharmacologiques prometteuses. Ceci nous a amené à développer …