Biomechanical properties of cancer cells

G Runel, N Lopez-Ramirez, J Chlasta, I Masse - Cells, 2021‏ - mdpi.com
Since the crucial role of the microenvironment has been highlighted, many studies have
been focused on the role of biomechanics in cancer cell growth and the invasion of the …

Multiscale mechanobiology in brain physiology and diseases

A Procès, M Luciano, Y Kalukula, L Ris… - Frontiers in Cell and …, 2022‏ - frontiersin.org
Increasing evidence suggests that mechanics play a critical role in regulating brain function
at different scales. Downstream integration of mechanical inputs into biochemical signals …

Automatic phase aberration compensation for digital holographic microscopy based on deep learning background detection

T Nguyen, V Bui, V Lam, CB Raub, LC Chang… - Optics express, 2017‏ - opg.optica.org
We propose a fully automatic technique to obtain aberration free quantitative phase imaging
in digital holographic microscopy (DHM) based on deep learning. The traditional DHM …

A 3D bioprinted in vitro model of neuroblastoma recapitulates dynamic tumor‐endothelial cell interactions contributing to solid tumor aggressive behavior

L Ning, J Shim, ML Tomov, R Liu, R Mehta… - Advanced …, 2022‏ - Wiley Online Library
Neuroblastoma (NB) is the most common extracranial tumor in children resulting in
substantial morbidity and mortality. A deeper understanding of the NB tumor …

Transformation of SH-SY5Y cell line into neuron-like cells: Investigation of electrophysiological and biomechanical changes

M Şahin, G Öncü, MA Yılmaz, D Özkan, H Saybaşılı - Neuroscience Letters, 2021‏ - Elsevier
Abstract SH-SY5Y human neuroblastoma cells are commonly used as neuronal models.
Here, we examined different aspects of SH-SY5Y cell differentiation. Various differentiation …

Measurements of morphological and biophysical alterations in individual neuron cells associated with early neurotoxic effects in Parkinson's disease

SA Yang, J Yoon, K Kim, YK Park - Cytometry part A, 2017‏ - Wiley Online Library
Parkinson's disease (PD) is a common neurodegenerative disease. However, therapeutic
methods of PD are still limited due to complex pathophysiology in PD. Here, optical …

Glutamate receptors and glioblastoma multiforme: an old “Route” for new perspectives

L Corsi, A Mescola, A Alessandrini - International journal of molecular …, 2019‏ - mdpi.com
Glioblastoma multiforme (GBM) is the most aggressive malignant tumor of the central
nervous system, with poor survival in both treated and untreated patients. Recent studies …

Chitin and carbon nanotube composites as biocompatible scaffolds for neuron growth

N Singh, J Chen, KK Koziol, KR Hallam, D Janas… - Nanoscale, 2016‏ - pubs.rsc.org
The design of biocompatible implants for neuron repair/regeneration ideally requires high
cell adhesion as well as good electrical conductivity. Here, we have shown that plasma …

Nanotoxicity of silver nanoparticles on HEK293T cells: A combined study using biomechanical and biological techniques

X Jiang, C Lu, M Tang, Z Yang, W Jia, Y Ma, P Jia… - ACS …, 2018‏ - ACS Publications
Human embryonic kidney 293T cells (HEK293T cells) before and after treatment with silver
nanoparticles (AgNPs) were measured using advanced atomic force microscopy (AFM) …

[HTML][HTML] Nanomechanics in monitoring the effectiveness of drugs targeting the cancer cell cytoskeleton

A Kubiak, T Zieliński, J Pabijan, M Lekka - International Journal of …, 2020‏ - mdpi.com
Increasing attention is devoted to the use of nanomechanics as a marker of various
pathologies. Atomic force microscopy (AFM) is one of the techniques that could be applied to …