Protein design: From the aspect of water solubility and stability

R Qing, S Hao, E Smorodina, D **, A Zalevsky… - Chemical …, 2022 - ACS Publications
Water solubility and structural stability are key merits for proteins defined by the primary
sequence and 3D-conformation. Their manipulation represents important aspects of the …

Peptide design and self-assembly into targeted nanostructure and functional materials

NJ Sinha, MG Langenstein, DJ Pochan… - Chemical …, 2021 - ACS Publications
Peptides have been extensively utilized to construct nanomaterials that display targeted
structure through hierarchical assembly. The self-assembly of both rationally designed …

Protein assembly by design

J Zhu, N Avakyan, A Kakkis, AM Hoffnagle… - Chemical …, 2021 - ACS Publications
Proteins are nature's primary building blocks for the construction of sophisticated molecular
machines and dynamic materials, ranging from protein complexes such as photosystem II …

De novo protein design, a retrospective

IV Korendovych, WF DeGrado - Quarterly reviews of biophysics, 2020 - cambridge.org
Proteins are molecular machines whose function depends on their ability to achieve
complex folds with precisely defined structural and dynamic properties. The rational design …

Chiral self-assembly of peptides: Toward the design of supramolecular polymers with enhanced chemical and biological functions

Y Shen, Y Wang, IW Hamley, W Qi, R Su… - Progress in Polymer …, 2021 - Elsevier
Chirality is one of the most important structural features in biological systems. Peptides, as a
class of small biomolecules, can self-assemble into various chiral supramolecular polymers …

Peptide nanotubes

IW Hamley - Angewandte Chemie International Edition, 2014 - Wiley Online Library
The self‐assembly of different classes of peptide, including cyclic peptides, amyloid peptides
and surfactant‐like peptides into nanotube structures is reviewed. The modes of self …

Peptide self-assembly for nanomaterials: the old new kid on the block

E De Santis, MG Ryadnov - Chemical Society Reviews, 2015 - pubs.rsc.org
Peptide self-assembly is an increasingly attractive tool for nanomaterials. Perfected in
biology peptide self-assembling systems have impacted on nearly any conceivable …

De novo design of self-assembling helical protein filaments

H Shen, JA Fallas, E Lynch, W Sheffler, B Parry… - Science, 2018 - science.org
We describe a general computational approach to designing self-assembling helical
filaments from monomeric proteins and use this approach to design proteins that assemble …

[HTML][HTML] De novo protein design: how do we expand into the universe of possible protein structures?

DN Woolfson, GJ Bartlett, AJ Burton, JW Heal… - Current opinion in …, 2015 - Elsevier
Highlights•The structural space explored by natural proteins is limited.•This raises questions:
what protein folds are possible, and how do we access them?•Parametric protein-design …

Protein Nanotubes as Advanced Material Platforms and Delivery Systems

B Liu, X Li, JP Zhang, X Li, Y Yuan, GH Hou… - Advanced …, 2024 - Wiley Online Library
Protein nanotubes (PNTs) as state‐of‐the‐art nanocarriers are promising for various
potential applications both in the food and pharmaceutical industries. Derived from edible …