Microbiota and maintenance of skin barrier function

TA Harris-Tryon, EA Grice - Science, 2022 - science.org
Human skin forms a protective barrier against the external environment and is our first line of
defense against toxic, solar, and pathogenic insults. Our skin also defines our outward …

Staphylococcus epidermidis and its dual lifestyle in skin health and infection

MM Severn, AR Horswill - Nature Reviews Microbiology, 2023 - nature.com
The coagulase-negative bacterium Staphylococcus epidermidis is a member of the human
skin microbiota. S. epidermidis is not merely a passive resident on skin but actively primes …

[HTML][HTML] Skin barrier function and the microbiome

HJ Lee, M Kim - International journal of molecular sciences, 2022 - mdpi.com
Human skin is the largest organ and serves as the first line of defense against environmental
factors. The human microbiota is defined as the total microbial community that coexists in the …

Fighting antibiotic resistance—strategies and (pre) clinical developments to find new antibacterials

S Walesch, J Birkelbach, G Jézéquel, FPJ Haeckl… - EMBO …, 2023 - embopress.org
Antibacterial resistance is one of the greatest threats to human health. The development of
new therapeutics against bacterial pathogens has slowed drastically since the approvals of …

Mass spectrometry-based metabolomics in microbiome investigations

A Bauermeister, H Mannochio-Russo… - Nature Reviews …, 2022 - nature.com
Microbiotas are a malleable part of ecosystems, including the human ecosystem.
Microorganisms affect not only the chemistry of their specific niche, such as the human gut …

The microbiome-sha** roles of bacteriocins

S Heilbronner, B Krismer, H Brötz-Oesterhelt… - Nature Reviews …, 2021 - nature.com
The microbiomes on human body surfaces affect health in multiple ways. They include not
only commensal or mutualistic bacteria but also potentially pathogenic bacteria, which can …

The skin microbiome: current landscape and future opportunities

P Smythe, HN Wilkinson - International journal of molecular sciences, 2023 - mdpi.com
Our skin is the largest organ of the body, serving as an important barrier against the harsh
extrinsic environment. Alongside preventing desiccation, chemical damage and …

Staphylococcus aureus colonisation and strategies for decolonisation

P Piewngam, M Otto - The Lancet Microbe, 2024 - thelancet.com
Staphylococcus aureus is a leading cause of death by infectious diseases worldwide.
Treatment of S aureus infections is difficult due to widespread antibiotic resistance …

Natural extracts for antibacterial applications

C Chen, L Chen, C Mao, L **, S Wu, Y Zheng, Z Cui… - Small, 2024 - Wiley Online Library
Bacteria‐induced epidemics and infectious diseases are seriously threatening the health of
people around the world. In addition, antibiotic therapy has been inducing increasingly more …

Systematic mining of the human microbiome identifies antimicrobial peptides with diverse activity spectra

AM King, Z Zhang, E Glassey, P Siuti, J Clardy… - Nature …, 2023 - nature.com
Human-associated bacteria secrete modified peptides to control host physiology and
remodel the microbiota species composition. Here we scanned 2,229 Human Microbiome …