Polymer scaffolds facilitate spinal cord injury repair

Q Zhang, B Shi, J Ding, L Yan, JP Thawani, C Fu… - Acta biomaterialia, 2019 - Elsevier
During the past decades, improving patient neurological recovery following spinal cord
injury (SCI) has remained a challenge. An effective treatment for SCI would not only reduce …

[HTML][HTML] Schwann cell-like cells: origin and usability for repair and regeneration of the peripheral and central nervous system

A Hopf, DJ Schaefer, DF Kalbermatten, R Guzman… - Cells, 2020 - mdpi.com
Functional recovery after neurotmesis, a complete transection of the nerve fiber, is often poor
and requires a surgical procedure. Especially for longer gaps (> 3 mm), end-to-end suturing …

[HTML][HTML] Development and in vitro differentiation of Schwann cells

SJ Hörner, N Couturier, DC Gueiber, M Hafner… - Cells, 2022 - mdpi.com
Schwann cells are glial cells of the peripheral nervous system. They exist in several
subtypes and perform a variety of functions in nerves. Their derivation and culture in vitro are …

Extracellular matrix components as therapeutics for spinal cord injury

AE Haggerty, MM Marlow, M Oudega - Neuroscience letters, 2017 - Elsevier
There is no treatment for people with spinal cord injury that leads to significant functional
improvements. The extracellular matrix is an intricate, 3-dimensional, structural framework …

Osseoperception following dental implant treatment: A systematic review

D Song, S Shujaat, C Politis, K Orhan… - Journal of Oral …, 2022 - Wiley Online Library
Objectives Osseoperception is defined as the ability to perceive tactile sensation via
mechanoreception in the peri‐implant environment. The objective was to systematically …

[HTML][HTML] Facial nerve regeneration via body-brain crosstalk: The role of stem cells and biomaterials

Y **e, C Ma, Q Zhu, T Fu, L Bai, X Lan, L Liu… - Neurobiology of …, 2024 - Elsevier
The human body is a complex, integral whole, and disruptions in one organ can lead to
dysfunctions in other parts of the organ network. The facial nerve, as the seventh cranial …

Conditioned medium-enriched umbilical cord mesenchymal stem cells: a potential therapeutic strategy for spinal cord injury, unveiling transcriptomic and secretomic …

R Subbarayan, D Murugan Girija, STK Raja… - Molecular Biology …, 2024 - Springer
Introduction Spinal cord injury (SCI) leads to significant destruction of nerve tissue, causing
the degeneration of axons and the formation of cystic cavities. This study aimed to examine …

Human umbilical cord derived mesenchymal stem cells in peripheral nerve regeneration

C Bojanic, K To, B Zhang, C Mak… - World journal of stem …, 2020 - pmc.ncbi.nlm.nih.gov
BACKGROUND Peripheral nerve injury can occur as a result of trauma or disease and
carries significant morbidity including sensory and motor loss. The body has limited ability …

[HTML][HTML] Endogenous extracellular vesicles participate in brain remodeling after ischemic stroke

MM Alvarez, FE Salazar, T Rodriguez… - International Journal of …, 2023 - mdpi.com
Brain remodeling after an ischemic stroke represents a promising avenue for exploring the
cellular mechanisms of endogenous brain repair. A deeper understanding of these …

Mesenchymal stem cells as a source of Schwann cells: their anticipated use in peripheral nerve regeneration

S Wakao, D Matsuse, M Dezawa - Cells Tissues Organs, 2015 - karger.com
Schwann cells form myelin, sustain axons and provide the microenvironment for nerve
fibers, thereby playing a key role in the peripheral nervous system (PNS). Schwann cells …