Vitamin B 6 is one of the most central molecules in cells of living organisms. It is a critical co-
factor for a diverse range of biochemical reactions that regulate basic cellular metabolism …

Research on major depression has confirmed that it is caused by an array of
biopsychosocial and lifestyle factors. Diet, exercise and sleep are three such influences that …

Globally populations are ageing. By 2050, it is estimated that there will be two billion people
aged 60 years or over, of which 131 million are projected to be affected by dementia, while …

Kynurenine (Kyn) pathway is a significant metabolic pathway of tryptophan (Trp). The
metabolites of the Kyn pathway are closely correlated with numerous diseases. Two main …

Insulin resistance (IR) underlines aging and aging-associated medical (diabetes, obesity,
dyslipidemia, hypertension) and psychiatric (depression, cognitive decline) disorders …

In recent years vitamin B6 has become a focus of research describing the compound's
critical function in cellular metabolism and stress response. For many years the sole function …

Background: B-vitamin deficiencies have been associated with depression; however, there
is very little prospective evidence from population-based studies of older adults. Objective …

The neuroendocrine theory of aging identified a cluster of conditions (hypertension, obesity,
dyslipidemia, diabetes type 2, menopause, late onset depression, vascular cognitive …

Background B vitamins have vital roles in the development, maintenance, and functioning of
the brain, while severe deficiencies have been linked to increased psychological disorders …

The importance of research into the possible role of dietary intake in depressive symptoms is
emphasized by the fact that diet is modifiable. We systematically reviewed observational …