Astrocyte reactivity and reactive astrogliosis: costs and benefits
Astrocytes are the most abundant cells in the central nervous system (CNS) that provide
nutrients, recycle neurotransmitters, as well as fulfill a wide range of other homeostasis …
nutrients, recycle neurotransmitters, as well as fulfill a wide range of other homeostasis …
Glial fibrillary acidic protein (GFAP) and the astrocyte intermediate filament system in diseases of the central nervous system
Glial fibrillary acidic protein (GFAP) is the hallmark intermediate filament (IF; also known as
nanofilament) protein in astrocytes, a main type of glial cells in the central nervous system …
nanofilament) protein in astrocytes, a main type of glial cells in the central nervous system …
Plasma glial fibrillary acidic protein is elevated in cognitively normal older adults at risk of Alzheimer's disease
Glial fibrillary acidic protein (GFAP), an astrocytic cytoskeletal protein, can be measured in
blood samples, and has been associated with Alzheimer's disease (AD). However, plasma …
blood samples, and has been associated with Alzheimer's disease (AD). However, plasma …
GFAP in health and disease
Glial fibrillary acidic protein (GFAP) is the main intermediate filament protein in mature
astrocytes, but also an important component of the cytoskeleton in astrocytes during …
astrocytes, but also an important component of the cytoskeleton in astrocytes during …
Astrocyte activation and reactive gliosis
M Pekny, M Nilsson - Glia, 2005 - Wiley Online Library
Astrocytes become activated (reactive) in response to many CNS pathologies, such as
stroke, trauma, growth of a tumor, or neurodegenerative disease. The process of astrocyte …
stroke, trauma, growth of a tumor, or neurodegenerative disease. The process of astrocyte …
Glial fibrillary acidic protein: GFAP-thirty-one years (1969–2000)
LF Eng, RS Ghirnikar, YL Lee - Neurochemical research, 2000 - Springer
It is now well established that the glial fibrillary acidic protein (GFAP) is the principal 8–9 nm
intermediate filament in mature astrocytes of the central nervous system (CNS). Over a …
intermediate filament in mature astrocytes of the central nervous system (CNS). Over a …
Heavy metals (Pb, Cd, As and MeHg) as risk factors for cognitive dysfunction: A general review of metal mixture mechanism in brain
Human exposure to toxic heavy metals is a global challenge. Concurrent exposure of heavy
metals, such as lead (Pb), cadmium (Cd), arsenic (As) and methylmercury (MeHg) are …
metals, such as lead (Pb), cadmium (Cd), arsenic (As) and methylmercury (MeHg) are …
Regulation of gliogenesis in the central nervous system by the JAK-STAT signaling pathway
A mechanism by which members of the ciliary neurotrophic factor (CNTF)–leukemia
inhibitory factor cytokine family regulate gliogenesis in the develo** mammalian central …
inhibitory factor cytokine family regulate gliogenesis in the develo** mammalian central …
Astrocyte biomarkers in Alzheimer's disease
Astrocytic contributions to Alzheimer's disease (AD) progression were, until recently, largely
overlooked. Astrocytes are integral to normal brain function and astrocyte reactivity is an …
overlooked. Astrocytes are integral to normal brain function and astrocyte reactivity is an …
Effects of neurotrophic factors in glial cells in the central nervous system: expression and properties in neurodegeneration and injury
Astrocytes, oligodendrocytes, and microglia are abundant cell types found in the central
nervous system and have been shown to play crucial roles in regulating both normal and …
nervous system and have been shown to play crucial roles in regulating both normal and …