[HTML][HTML] An overview of current COVID-19 vaccine platforms

A Nagy, B Alhatlani - Computational and structural biotechnology journal, 2021 - Elsevier
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for the
coronavirus disease 2019 (COVID-19) pandemic that emerged in December 2019 in Wuhan …

A comparison between SARS-CoV-1 and SARS-CoV2: an update on current COVID-19 vaccines

G Abdolmaleki, MA Taheri, S Paridehpour… - DARU Journal of …, 2022 - Springer
Since the outbreak of the novel coronavirus disease 2019 (COVID-19) in Wuhan, China,
many health care systems have been heavily engaged in treating and preventing the …

Vectored immunotherapeutics for infectious diseases: Can rAAVs be the game changers for fighting transmissible pathogens?

W Zhan, M Muhuri, PWL Tai, G Gao - Frontiers in immunology, 2021 - frontiersin.org
Conventional vaccinations and immunotherapies have encountered major roadblocks in
preventing infectious diseases like HIV, influenza, and malaria. These challenges are due to …

Irradiation activates MZF1 to inhibit miR-541-5p expression and promote epithelial-mesenchymal transition (EMT) in radiation-induced pulmonary fibrosis (RIPF) by …

X Liang, Z Yan, P Wang, Y Liu, X Ao, Z Liu… - International Journal of …, 2021 - mdpi.com
Understanding miRNAs regulatory roles in epithelial-mesenchymal transition (EMT) would
help establish new avenues for further uncovering the mechanisms underlying radiation …

Concepts to reveal parvovirus–nucleus interactions

S Mattola, S Hakanen, S Salminen, V Aho, E Mäntylä… - Viruses, 2021 - mdpi.com
Parvoviruses are small single-stranded (ss) DNA viruses, which replicate in the nucleoplasm
and affect both the structure and function of the nucleus. The nuclear stage of the parvovirus …

Adeno-associated viral (AAV) vector-mediated therapeutics for diabetic cardiomyopathy–current and future perspectives

D Prakoso, M Tate, MJD Blasio, RH Ritchie - Clinical Science, 2021 - portlandpress.com
Diabetes increases the prevalence of heart failure by 6–8-fold, independent of other
comorbidities such as hypertension and coronary artery disease, a phenomenon termed …

Delving into revolutionary SARS-CoV-2 vaccine approaches: Molecular and virological examinations; principles of SARS-CoV-2 vaccine platform

F Edalat, FH Tabatabaie, A Moattari, A Letafati… - Vacunas (English …, 2024 - Elsevier
Abstract Coronavirus disease (COVID-19) is an infectious illness caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2). It emerged in 2019 and quickly became …

Gene therapies and COVID-19 vaccines: a necessary discussion in relation with viral vector-based approaches

A Aledo-Serrano, A Gil-Nagel, J Isla… - Orphanet Journal of …, 2021 - Springer
The COVID-19 pandemic is adding an unanticipated concern for those affected by genetic
diseases. Most of the new treatment achievements for these patients are made possible as a …

Single-shot rAAV5-based vaccine provides long-term protective immunity against SARS-CoV-2 and its variants

G Liao, X Fan, H Lau, Z Liu, C Li, Z Xu, Y Zhang, X Qi… - bioRxiv, 2021 - biorxiv.org
The COVID-19 pandemic and the SARS-CoV-2 with its variants have posed unprecedented
challenges worldwide. Existing vaccines have limited effectiveness against the SARS-CoV-2 …

[PDF][PDF] CELL & GENE THERAPY INSIGHTS

I INSIGHT - researchgate.net
Cancer remains a devastating global public health challenge. Scientific research has
focused on gaining an enhanced understanding of disease, genomics and molecular …