Abstract Type 2 diabetes (T2DM) is a persistent metabolic disorder rising rapidly worldwide.
It is characterized by pancreatic insulin resistance and β-cell dysfunction. Hyperglycemia …

Pathogenesis of type 2 diabetes mellitus (T2DM) and development of insulin resistance are
characterized by multi‐stimuli factors notably glucolipotoxicity, generation of reactive oxygen …

Diabetes mellitus is a metabolic disorder that majorly affects the endocrine gland, and it is
symbolized by hyperglycemia and glucose intolerance owing to deficient insulin secretory …

Oxidative stress has been considered as a major hallmark for the pathogenesis and
development of type 2 diabetes mellitus (T2DM), but still it is debatable whether it is a mere …

Background Insulin resistance (IR) is one of the major hallmark for pathogenesis and
etiology of type 2 diabetes mellitus (T2DM). IR is directly interlinked with various …

Alzheimer's disease (AD) is one of the most common neurodegenerative diseases. Its major
pathological hallmarks, neurofibrillary tangles (NFT), and amyloid-β plaques can result from …

ABSTRACT Interleukin-6 (IL-6) is a proinflammatory cytokine that decisively induces the
development of insulin resistance and pathogenesis of type 2 diabetes mellitus (T2DM) …

In the last two decades, numerous in vitro studies demonstrated that insulin receptors and
theirs downstream pathways are widely distributed throughout the brain. This evidence has …

The increasing demand for natural products as an alternative therapy for chronic diseases
has encouraged research into the pharmacological importance of bioactive compounds from …

Type 2 diabetes (T2DM), Alzheimer's disease (AD), and insulin resistance are age‐related
conditions and increased prevalence is of public concern. Recent research has provided …