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Environmental and health impacts of graphene and other two-dimensional materials: a graphene flagship perspective
Two-dimensional (2D) materials have attracted tremendous interest ever since the isolation
of atomically thin sheets of graphene in 2004 due to the specific and versatile properties of …
of atomically thin sheets of graphene in 2004 due to the specific and versatile properties of …
Understanding the chemical exposome during fetal development and early childhood: a review
M Krausová, D Braun… - Annual Review of …, 2023 - annualreviews.org
Early human life is considered a critical window of susceptibility to external exposures.
Infants are exposed to a multitude of environmental factors, collectively referred to as the …
Infants are exposed to a multitude of environmental factors, collectively referred to as the …
Trophoblast stem cell-based organoid models of the human placental barrier
Human placental villi have essential roles in producing hormones, mediating nutrient and
waste exchange, and protecting the fetus from exposure to xenobiotics. Human trophoblast …
waste exchange, and protecting the fetus from exposure to xenobiotics. Human trophoblast …
3D in vitro blood‐brain‐barrier model for investigating barrier insults
Abstract Blood‐brain‐barrier (BBB) disruption has been associated with a variety of central‐
nervous‐system diseases. In vitro BBB models enable to investigate how the barrier reacts …
nervous‐system diseases. In vitro BBB models enable to investigate how the barrier reacts …
Revolutionizing the female reproductive system research using microfluidic chip platform
J Yan, T Wu, J Zhang, Y Gao, JM Wu… - Journal of …, 2023 - Springer
Comprehensively understanding the female reproductive system is crucial for safeguarding
fertility and preventing diseases concerning women's health. With the capacity to simulate …
fertility and preventing diseases concerning women's health. With the capacity to simulate …
Placenta-on-a-chip as an in vitro approach to evaluate the physiological and structural characteristics of the human placental barrier upon drug exposure: a systematic …
FA Elzinga, B Khalili, DJ Touw, JR Prins… - Journal of Clinical …, 2023 - mdpi.com
Quantification of fetal drug exposure remains challenging since sampling from the placenta
or fetus during pregnancy is too invasive. Currently existing in vivo (eg, cord blood sampling) …
or fetus during pregnancy is too invasive. Currently existing in vivo (eg, cord blood sampling) …
Advances in cell coculture membranes recapitulating in vivo microenvironments
Porous membranes play a critical role in in vitro heterogeneous cell coculture systems
because they recapitulate the in vivo microenvironment to mediate physical and biochemical …
because they recapitulate the in vivo microenvironment to mediate physical and biochemical …
[HTML][HTML] Investigating and modelling an engineered millifluidic in vitro oocyte maturation system reproducing the physiological ovary environment in the sheep model
A Mastrorocco, L Cacopardo, L Temerario, NA Martino… - Cells, 2022 - mdpi.com
In conventional assisted reproductive technologies (ARTs), oocytes are in vitro cultured in
static conditions. Instead, dynamic systems could better mimic the physiological in vivo …
static conditions. Instead, dynamic systems could better mimic the physiological in vivo …
RISING STARS: Approaches to modeling placental function in preeclampsia in vitro and in vivo
Modeling preeclampsia remains difficult due to the nature of the disease and the unique
characteristics of the human placenta. Members of the Hominidae superfamily have a villous …
characteristics of the human placenta. Members of the Hominidae superfamily have a villous …
Critical design parameters to develop biomimetic organ-on-a-chip models for the evaluation of the safety and efficacy of nanoparticles
M Abdelkarim, L Perez-Davalos… - Expert Opinion on …, 2023 - Taylor & Francis
Introduction Organ-on-a-chip (OOC) models are based on microfluidics and can recapitulate
the healthy and diseased microstructure of organs1 and tissues and the dynamic …
the healthy and diseased microstructure of organs1 and tissues and the dynamic …