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[HTML][HTML] Pharmaceutical drugs and natural therapeutic products for the treatment of type 2 diabetes mellitus
J Blahova, M Martiniakova, M Babikova, V Kovacova… - Pharmaceuticals, 2021 - mdpi.com
Type 2 diabetes mellitus (T2DM) is the most widespread form of diabetes, characterized by
chronic hyperglycaemia, insulin resistance, and inefficient insulin secretion and action …
chronic hyperglycaemia, insulin resistance, and inefficient insulin secretion and action …
Human nitric oxide synthase—Its functions, polymorphisms, and inhibitors in the context of inflammation, diabetes and cardiovascular diseases
In various diseases, there is an increased production of the free radicals needed to carry out
certain physiological processes but their excessive amounts can cause oxidative stress and …
certain physiological processes but their excessive amounts can cause oxidative stress and …
Adipose organ dysfunction and type 2 diabetes: Role of nitric oxide
Adipose organ, historically known as specialized lipid-handling tissue serving as the long-
term fat depot, is now appreciated as the largest endocrine organ composed of two main …
term fat depot, is now appreciated as the largest endocrine organ composed of two main …
Rational design to improve the catalytic efficiency and stability of arginine deiminase
Y Zhang, T Zhang, M Li, M Miao - International Journal of Biological …, 2024 - Elsevier
Arginine deiminase (ADI) has garnered significant interest because of its ability to
objectively eradicate cancer cells and produce L-citrulline. To meet the production demands …
objectively eradicate cancer cells and produce L-citrulline. To meet the production demands …
Metabolic regulation of glucagon secretion
Since the discovery of glucagon 100 years ago, the hormone, and the pancreatic islet alpha
cells that produce it, have remained enigmatic relative to insulin producing beta cells …
cells that produce it, have remained enigmatic relative to insulin producing beta cells …
Metabolic effects of L‐citrulline in type 2 diabetes
The prevalence of type 2 diabetes (T2D) is increasing worldwide. Decreased nitric oxide
(NO) bioavailability is involved in the pathophysiology of T2D and its complications. l …
(NO) bioavailability is involved in the pathophysiology of T2D and its complications. l …
[HTML][HTML] Measurement of pulsatile insulin secretion: Rationale and methodology
Pancreatic β-cells are responsible for the synthesis and exocytosis of insulin in response to
an increase in circulating glucose. Insulin secretion occurs in a pulsatile manner, with …
an increase in circulating glucose. Insulin secretion occurs in a pulsatile manner, with …
Impact of different hormones on the regulation of nitric oxide in diabetes
Polymetabolic syndrome achieved pandemic proportions and dramatically influenced public
health systems functioning worldwide. Chronic vascular complications are the major …
health systems functioning worldwide. Chronic vascular complications are the major …
Neurotransmitters regulate β cells insulin secretion: a neglected factor
CC Kong, JD Cheng, W Wang - World Journal of Clinical …, 2023 - pmc.ncbi.nlm.nih.gov
β cells are the main cells responsible for the hypoglycemic function of pancreatic islets, and
the insulin secreted by these cells is the only hormone that lowers blood glucose levels in …
the insulin secreted by these cells is the only hormone that lowers blood glucose levels in …
Effects of l-citrulline supplementation and watermelon consumption on longer-term and postprandial vascular function and cardiometabolic risk markers: a meta …
l-Citrulline may improve non-invasive vascular function and cardiometabolic risk markers
through increases in l-arginine bioavailability and nitric oxide synthesis. A meta-analysis of …
through increases in l-arginine bioavailability and nitric oxide synthesis. A meta-analysis of …