Astroglia are a broad class of neural parenchymal cells primarily dedicated to homoeostasis
and defence of the central nervous system (CNS). Astroglia contribute to the …

Reactive astrocytes are astrocytes undergoing morphological, molecular, and functional
remodeling in response to injury, disease, or infection of the CNS. Although this remodeling …

Reactive astrocytes play an important role in neurological diseases, but their molecular and
functional phenotypes in epilepsy are unclear. Here, we show that in patients with temporal …

Epilepsy affects~ 65 million people worldwide. First-line treatment options include> 20
antiseizure medications, but seizure control is not achieved in approximately one-third of …

Epilepsy remains a major health concern as anti-seizure medications frequently fail, and
there is currently no treatment to stop or prevent epileptogenesis, the process underlying the …

Epilepsy is a neurological disorder afflicting~ 65 million people worldwide. It is caused by
aberrant synchronized firing of populations of neurons primarily due to imbalance between …

Microglia are the resident macrophages of the central nervous system. They play key roles
in brain development, and physiology during life and aging. Equipped with a variety of …

Astrocytes are key cellular partners for neurons in the central nervous system. Astrocytes
react to virtually all types of pathological alterations in brain homeostasis by significant …

Astrocytes are highly efficient homeostatic glial cells playing a crucial role in optimal brain
functioning and homeostasis. Astrocytes respond to changes in brain homoeostasis …

The neurone-centred view of the past disregarded or downplayed the role of astroglia as a
primary component in the pathogenesis of neurological diseases. As this concept is …