Multimodal non-invasive non-pharmacological therapies for chronic pain: mechanisms and progress

Y Shi, W Wu - BMC medicine, 2023‏ - Springer
Background Chronic pain conditions impose significant burdens worldwide.
Pharmacological treatments like opioids have limitations. Non-invasive non …

Advances in targeting central sensitization and brain plasticity in chronic pain

AH Bazzari, FH Bazzari - The Egyptian Journal of Neurology, Psychiatry …, 2022‏ - Springer
Maladaptation in sensory neural plasticity of nociceptive pathways is associated with various
types of chronic pain through central sensitization and remodeling of brain connectivity …

One size does not fit all: towards optimising the therapeutic potential of endogenous pain modulatory systems

K Bannister, S Hughes - Pain, 2023‏ - journals.lww.com
Top–down processing pathways modulate neuronal transmission at the level of the spinal
cord dorsal horn and thus govern, in part, the percept of pain. In health, these descending …

[HTML][HTML] Medical extended reality trials: Building robust comparators, controls, and sham

S Persky, L Colloca - Journal of Medical Internet Research, 2023‏ - jmir.org
The explosive pace of development and research in medical extended reality (MXR) is a
testament to its promise for health care and medicine. In comparison with this growth, there …

Reliability of quantitative sensory testing in the assessment of somatosensory function after high-frequency stimulation–induced sensitisation of central nociceptive …

H Fawsitt-Jones, J Vollert, O O'Daly, SCR Williams… - Pain, 2024‏ - journals.lww.com
The high frequency stimulation (HFS) model can be used alongside quantitative sensory
testing (QST) to assess the sensitisation of central nociceptive pathways. However, the …

The impact of an immersive digital therapeutic tool on experimental pain: a pilot randomized within-subject experiment with an active control condition

S Diallo, S Marchand, A Dumais… - Frontiers in Pain Research, 2024‏ - frontiersin.org
Background Pain is a complex and multifaced sensory and emotional experience. Virtual
reality (VR) has shown promise in reducing experimental pain and chronic pain. This study …

A systematic review and meta-analysis of non-pharmacological methods to manipulate experimentally induced secondary hypersensitivity

GJ Bedwell, PC Chikezie, FT Siboza, L Mqadi… - The Journal of …, 2023‏ - Elsevier
This systematic review and meta-analysis investigated the effects of non-pharmacological
manipulations on experimentally induced secondary hypersensitivity in pain-free humans …

Investigating the influence of experimentally induced central sensitisation on pain prediction error encoding in healthy individuals: a novel virtual reality protocol

F Palmisani, JSP Thiyagarajan, J Horsey, SW Hughes… - bioRxiv, 2025‏ - biorxiv.org
Persistent mismatches between predicted and actual pain-related signals, namely prediction
errors (PEs), can cause maladaptive overestimation of pain intensity, a common feature of …

Dynamické změny centrální reaktibility v kontextu fyzioterapeutické praxe

J Brokešová - 2023‏ - dspace.cuni.cz
Název práce: Dynamické změny centrální reaktibility v kontextu fyzioterapeutické praxe Cíl
práce: Cílem této diplomové práce je vyhledat, utřídit a shrnout dosavadní poznatky o …

慢性肌肉骨骼疼痛病人中枢敏化的研究进展.

**瑞娟, 张俊娟, 张士变, **佳佳… - Chinese Nursing …, 2023‏ - search.ebscohost.com
慢性肌肉骨骼疼痛病人中枢敏化的研究进展 Page 1 CHINESE NURSING RESEARCH May,2023
Vol. 37 No. 10 慢性肌肉骨骼疼痛病人中枢敏化的研究进展 **瑞娟1,张俊娟2*,张士变1,**佳佳2,贾 …