Noninvasive medical neuroimaging has yielded many discoveries about the brain
connectivity. Several substantial techniques map** morphological, structural and …

Background: Analysis of the human connectome using functional magnetic resonance
imaging (fMRI) started in the mid-1990s and attracted increasing attention in attempts to …

Diffusion magnetic resonance imaging (dMRI) tractography is an advanced imaging
technique that enables in vivo reconstruction of the brain's white matter connections at …

Immune processes have a vital role in CNS homeostasis, resilience and brain reserve. Our
cognitive and social abilities rely on a highly sensitive and fine-tuned equilibrium of immune …

Cerebral small vessel disease (SVD) is commonly observed on neuroimaging among
elderly individuals and is recognized as a major vascular contributor to dementia, cognitive …

Neuroinflammation is a pathophysiological hallmark of multiple sclerosis and has a close
mechanistic link to neurodegeneration. Although this link is potentially targetable, robust …

Fatigue is one of the most common debilitating symptoms reported by persons with multiple
sclerosis (MS). It reflects feelings of tiredness, lack of energy, low motivation, and difficulty in …

How the human brain works is still a question, as is its implication with brain architecture: the
non-trivial structure–function relationship. The main hypothesis is that the anatomic …

Multiple sclerosis is a neuroinflammatory and neurodegenerative disorder of the central
nervous system that can be considered a network disorder. In MS, lesional pathology …

A review of physical and mathematical methods for reconstructing the functional networks of
the brain based on recorded brain activity is presented. Various methods are considered, as …