Plants derived therapeutic strategies targeting chronic respiratory diseases: Chemical and immunological perspective

P Prasher, M Sharma, M Mehta, KR Paudel… - Chemico-biological …, 2020 - Elsevier
The apparent predicament of the representative chemotherapy for managing respiratory
distress calls for an obligatory deliberation for identifying the pharmaceuticals that effectively …

Membrane trafficking alterations in breast cancer progression

A Ferreira, P Castanheira, C Escrevente… - Frontiers in Cell and …, 2024 - frontiersin.org
Breast cancer (BC) is the most common type of cancer in women, and remains one of the
major causes of death in women worldwide. It is now well established that alterations in …

Phagocytosis mediated by scavenger receptor class BI promotes macrophage transition during skeletal muscle regeneration

J Zhang, C Qu, T Li, W Cui, X Wang, J Du - Journal of Biological Chemistry, 2019 - jbc.org
Macrophages play an essential role in skeletal muscle regeneration. The phagocytosis of
muscle cell debris induces a switch of pro-inflammatory macrophages into an anti …

[HTML][HTML] Promotion of osteochondral repair through immune microenvironment regulation and activation of endogenous chondrogenesis via the release of apoptotic …

G Tian, H Yin, J Zheng, R Yu, Z Ding, Z Yan, Y Tang… - Bioactive Materials, 2024 - Elsevier
Utilizing transplanted human umbilical cord mesenchymal stem cells (HUMSCs) for cartilage
defects yielded advanced tissue regeneration, but the underlying mechanism remain …

Inhibition of EZH2 methyltransferase decreases immunoediting of mesothelioma cells by autologous macrophages through a PD-1–dependent mechanism

M Hamaidia, H Gazon, C Hoyos, GB Hoffmann… - JCI …, 2019 - pmc.ncbi.nlm.nih.gov
The roles of macrophages in orchestrating innate immunity through phagocytosis and T
lymphocyte activation have been extensively investigated. Much less understood is the …

Farnesoid X receptor regulates lung macrophage activation and injury following nitrogen mustard exposure

A Murray, T Banota, GL Guo, LC Smith… - Toxicology and applied …, 2022 - Elsevier
Nitrogen mustard (NM) is a cytotoxic vesicant known to cause acute lung injury which
progresses to fibrosis; this is associated with a sequential accumulation of pro-and anti …

Wu-Mei-Wan ameliorates murine ulcerative colitis by regulating macrophage polarization

S Yan, H Wei, R Jia, M Zhen, S Bao, W Wang… - Frontiers in …, 2022 - frontiersin.org
An increasing body of evidence shows that macrophages play an important role in the
pathogenesis of ulcerative colitis (UC). Macrophage polarization and changes in related …

[HTML][HTML] Unraveling the relevance of ARL GTpases in cutaneous melanoma prognosis through integrated bioinformatics analysis

C Brito, B Costa-Silva, DC Barral, M Pojo - International journal of …, 2021 - mdpi.com
Cutaneous melanoma (CM) is the deadliest skin cancer, whose molecular pathways
underlying its malignancy remain unclear. Therefore, new information to guide evidence …

Alteration of tumor-associated macrophage subtypes mediated by KRT6A in pancreatic ductal adenocarcinoma

J Zhang, H Sun, S Liu, W Huang, J Gu… - Aging (Albany …, 2020 - pmc.ncbi.nlm.nih.gov
Pancreatic ductal adenocarcinoma (PDAC) is severely affecting the health and lives of
patients. Clarifying the composition and regulatory factors of tumor immune …

Quantitative Proteomic Analysis of Macrophages Infected with Trypanosoma cruzi Reveals Different Responses Dependent on the SLAMF1 Receptor and the Parasite …

A Herreros-Cabello… - International …, 2024 - pmc.ncbi.nlm.nih.gov
Chagas disease is caused by the intracellular protozoan parasite Trypanosoma cruzi. This
disease affects mainly rural areas in Central and South America, where the insect vector is …