Fibronectin (FN) is a ubiquitous extracellular matrix (ECM) glycoprotein that plays vital roles
during tissue repair. The plasma form of FN circulates in the blood, and upon tissue injury, is …

In the process of matrix assembly, multivalent extracellular matrix (ECM) proteins are
induced to self-associate and to interact with other ECM proteins to form fibrillar networks …

Fibronectin (FN) is a multidomain protein with the ability to bind simultaneously to cell
surface receptors, collagen, proteoglycans, and other FN molecules. Many of these domains …

A notable challenge for the design of engineered living materials (ELMs) is programming a
cellular system to assimilate resources from its surroundings and convert them into …

Background Vasculogenic mimicry (VM) has been reported in various malignant tumours
and is known to play an important role in cancer progression and metastasis. However, the …

During cancer progression, the extracellular matrix (ECM) undergoes dramatic changes,
which promote cancer cell migration and invasion. In the remodeled tumor ECM, the …

In addition to soluble factors, the extracellular matrix (ECM) also plays a vital role in normal
vasculogenesis and in the pathological angiogenesis of many disease states. Here we will …

Alterations in the abundance or activities of alternative splicing regulators generate
alternatively spliced variants that contribute to multiple aspects of tumor establishment …

Robust neovascularization and lymphangiogenesis have been found in a variety of
aggressive and metastatic tumors. Endothelial sprouting angiogenesis is generally …

Abstract MULTIMERIN2 (MMRN2), also known as Endoglyx-1, is an extracellular matrix
glycoprotein whose function has so far remained elusive. Given its specific localization in …